The allele for sickle anemia is found at higher frequencies in central Africa than in other parts of the world. What are the advantage and disadvantages?
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The allele for sickle anemia is found at higher frequencies in central Africa than in other parts of the world. What are the advantage and disadvantages?
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- What would happen to the frequency of heterozygous carriers of sickle-cell anemia (with AS genotype) if mosquitoes were completely wiped out in a large region?Explain the High frequency of the sickle-cell allele HbβS in regions of Africa where malaria is prevalent?What is the frequency of sickle cell disease (anemia)? https://ghr.nlm.nih.gov/condition/sickle-cell-disease#inheritance https://www.cdc.gov/ncbddd/sicklecell/traits.html
- What is sickle cell anemia? What is the true inheritance pattern? How did scientists discover the true inheritance pattern?What advantage is there for individuals that are heterozygous for the sickle cell character?What is heterozygote advantage. How does this phenomenon explain the preponderance of disorders such as cystic fibrosis and sickle cell anemia ?
- What is the heterozygous advantage of people having sickle-cell trait in areas where malaria is a major cause of death?1. What are the symptoms of sickle cell disease (anemia)? 2. What is the genotype of sickle cell disease? Use these sources to find the answers: https://ghr.nlm.nih.gov/condition/sickle-cell-disease#inheritance https://www.cdc.gov/ncbddd/sicklecell/traits.htmlIf, within specific regional populations over two thousand years ago, sickle-cell anemia killed those individuals born with it before they could reproduce to pass it on to offspring, how did it persist in these populations? Group of answer choices A-Because of late-onset of the disease. B-Because it is cause by a virus and it spreads faster than people died. C-Because of the basic principles of mendelian inheritance that result in some heterozygote "carrier" combinations. D-Because malaria made it possible to survive sickle cell anemia since the parasite would carry oxygen on the blood cells with the mutated hemoglobin. E-It does not persist. Natural selection removes the allele because people die from both malaria and sickle-cell anemia.
- Describe the phenotype of individuals who inherit two copies of the HbS allele-Sickle Cell Disease. ( find a source to support the information)The farmers in La Trinidad, Benguet have a remarkable ability to work in the cold without gloves and not suffer decreased skin blood flow. Does this prove that there is a genetic difference between the farmers in La Trinidad and the other people with regard to this characteristic?Explain the differences between an individual homozygous for the sickle hemoglobin allele (HbS/HbS) and one who is heterozygous (HbA/HbS). Consider the hemoglobin molecule, cells, and disease.
