Synthesis of Ibuprofen-Part 2: 1. Some pain relievers including ibuprofen (MotrinⓇ) and naproxen (AleveⓇ) are "α-arylpropanoic acids." Look up the structure of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis. F 2. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What reaction steps would need to change and how?
Synthesis of Ibuprofen-Part 2: 1. Some pain relievers including ibuprofen (MotrinⓇ) and naproxen (AleveⓇ) are "α-arylpropanoic acids." Look up the structure of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis. F 2. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What reaction steps would need to change and how?
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter10: Alcohols
Section: Chapter Questions
Problem 10.50P
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Please answer in detail and show all your work, thank you! Synthesis of Ibuprofen-Part 2: Some pain relievers including ibuprofen (Motrin ® and naproxen (Aleve B are " α-arylpropanoic acids." Look up the structure of flurbiprofen, another α-arylpropionic acid. Using the same reactions that we used for making ibuprofen, show how to make flurbiprofen from the compound below. Show all intermediates and reagents in your synthesis. Show how you would prepare ibuprofen starting from p-isobutylbenzaldehyde rather than p-isobutylacetophenenone. What reaction steps would need to change and how?
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