Question 3 (1 pt): Which positions in adenine and guanine have the potential to form hydrogen bonds but are not involved in Watson-Crick base pairing? What might this be used for?
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Question 3 (1 pt): Which positions in adenine and guanine have the potential to form hydrogen bonds
but are not involved in Watson-Crick base pairing? What might this be used for?
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- HN N C N H₂N HN پرسپولیو D B CH₂ -N N NH₂ E When part of a nucleotide in a nucleic acid chain, which of the following may base pair with thymine nucleotides? Choose all correct answers and assume normal Watson-Crick base pairing.Question Guide: 1. Name and write the structures of the purine and pyrimidine bases present in DNA. Purine Рyrimidine Structures: Purine PyrimidineN. NH 2. One of the key pieces of information that Watson and Crick used in determining the secondary structure of DNA came from experiments done by E. Chargaff, in which he studied the nucleotide composition of DNA from many different species. O=P-OCH, N. `NH, HN он O= P- OCH, NH, Chargaff noted that the molar quantity of A_was always approximately equal to the molar quantity of T. and the molar quantity of C was always approximately equal to the molar quantity of G. How were Chargaff's results explained by the structural model of DNA proposed by Watson and Crick? N OH N. O= P-OCH, OH OH
- Question 3: Look carefully at the structures of the two molecules shown below and answer the following questions. O= ddCTP O= OH O 11 HO-P-O-P-O-P-O I OH OH NH₂ ddCMP O 11 HO-P-O OH NH₂ A) What would you expect to happen if you added ddCTP to a DNA synthesis reaction in vitro in large excess over the concentration of dCTP? B) What would happen if ddCTP were added at 10% of the concentration of dCTP? C) What effect would you expect if ddCMP were added to the synthesis in large excess over dCTP? At 10% of the concentration of dCTP?52. Which of the following base pairings is CORRECT? Group of answer choices C-T A-C C-G A-GQuestion: Which base (A, C, T or G) corresponds to X in the unknown? I did the experiment, got the data below, and calculated the binding constants. But I am TOTALLY lost as to how to figure this out! I don't even know what steps I would take. Base pairs Data – all had Temp = 250C PH = 7 Binding Constant A & X [A] = 0.00373221M [X] = 0.00373221M [AX] = 0.0462678M 3.322 C & X [C] = 0.0469007M [X] = 0.0469007M [CX] = 0.00309935M 1.409 T & X [T] = 0.0452279M [X] = 0.0452279M [TX] = 0.00477212M 2.333 G & X [G] = 0.0469554M [X] = 0.0469554M [GX] = 0.00304456M 2.633
- Question 5. If all the nucleotide sugar in a DNA molecule have the following conformation, do you think this DNA is in A form, B form, or Z form? Must justify your answer. What do we call this conformation? O. 2' C5 Base 7.0 A 3' P.The specificity of Watson-Crick nucleobase pairing enables the biological information to be encoded and passed down through generations of cells and organisms. This specificity arises from the chemical structure of the base pairs, namely the pattern of hydrogen bond donors and acceptors that stabilize only two pairing interactions] relative to the others. How many possible pairwise interactions could potentially exist at a single position within a sequence, including the correct pairs, and all possible other combinations of DNA bases?Amino acids have an average molar mass of 100 g/mol.How many bases on a single strand of DNA are needed to codefor a protein with a molar mass of 5x10^5g/mol?
- Question:- What is the average radius of a piece of double-stranded DNA in water that has a link length of 5.9 nm and and is 3019228 links long? If the two strands of the double-stranded DNA are separated, each chain now has a radius of 871 nm. What is the link length for single-stranded DNA?In human DNA, 70% of cytosine residues that are followed by guanine (so-called CpG dinucleotides, where p indicates the phosphate in the phosphodiester bond between these two nucleotides) are methylated to form 5-methylcytosine. As shown in the following figure, if 5-methylcytosine should undergo spontaneous deamination, it becomes thymine. 2. NH, Deamination 5-methylcytosine Thymine Methylated CpG dinucleotides are hotspots for point mutations in human DNA. Can you propose a hypothesis that explains why?Choose all of the statements that correctly describe the base pairs drawn below. A C H H-N -H-N N-H- -N B H D موعة Rita N -H---- 2 NHN O- -H-N H -H- N- -H-N The non-Watson-Crick base pair shown in A is much less stable than the base pairs shown in B and C, because the smaller size of the two pyrimidine bases induces a distortion in the structure of the double helix that decreases the stability of the helix when compared to helices with the normal Watson-Crick base pairs. The base pair shown in B is found in BOTH DNA and RNA The base pair shown in C is found ONLY in RNA and NOT DNA The base pair seen in B is more stable than the Watson-Crick base pair shown in C partly because of a larger number of hydrogen bonds and partly because of more favourable pi-stacking interactions with adjacent base pairs.