ОН triosephosphate isomerase 2-0,PO. HO dihydroxyacetone phosphate H 2-0,PO. glyceraldehyde-3-phosphate
Q: Glutamate dehydrogenase functions to produce ammonia for the urea cycle. Use the standard reduction…
A: Glutamate dehydrogenase is the enzyme that is responsible for the production of ammonia. Ammonia…
Q: Assume that you have a solution of 0.1 M glucose 6-phosphate. To this solu- tion you add the enzyme…
A: An enzyme is a substance that acts as a catalyst in living organisms, regulating the rate at which…
Q: 5-phosphate) and an aldopentose (ribose-5-phosphate) to an aldotriose (glyceraldehyde-3-phosphate)…
A: TPP is the co-enzyme of this reaction where the enzyme is transketolase. The products that are…
Q: Glyphosphate(commercially available as Roundup) is an analog of phosphoenolpyruvate that acts as a…
A: Amino acids are the basic units that make up proteins. Amino acids are comprised of carbon,…
Q: The turnover number of the enzyme fumarase that catalyzes the reaction,
A: Enzymes are highly specialized proteins that have extraordinary catalytic power, greater than that…
Q: The activity of an enzyme requires a glutamic acid to display its -COOHfunctional group in the…
A: The enzyme is considered as the catalytic protein, which has the active site at which it binds the…
Q: In a major metabolic pathway involving the monosaccharide glucose, one of the reactions involve the…
A: The given reaction is a part of the glycolysis pathway. During glycolysis, glucose is first…
Q: What product is formed when dihydroxyacetone phosphate is reacted with NADH in the presence of the…
A: Glycerol-3-phosphate dehydrogenase (GPDH) converts dihydroxyacetone phosphate (DHAP) to…
Q: A reaction involved in the metabolism of sugars is the splitting of fructose-1,6-diphosphate to give…
A: Glycolysis is the process by which one molecule of glucose is converted into two molecules of…
Q: Human blood serum contains a class of enzymes known as acid phosphatases, which hydrolyze biological…
A: Acid phosphatases are the hydrolytic enzymes that release phosphate ions from various substrates.…
Q: Seduheptulose is an intermediate in respiratory and photosynthetic pathways and plays a vital role…
A: a. The stable form of sugars like pentose and hexose sugars are five or six-atom rings and these…
Q: Dicyclohexylcarbodiimide (DCCD) is a reagent that reacts with Asp or Glu residues. Explain why the…
A: The process of breakdown of glucose to generate the energy molecule adenosine triphosphate (ATP) is…
Q: For the following aspartate reaction in the presence of inhibitor, Km = 0.00065 M. Determine Vmax in…
A: Enzymes are usually protein molecules which catalyzes biochemical reaction by decreasing the…
Q: Saccharide X occurs in the roots of several species of plants. Deduce the structure of saccharide x…
A: Saccharide means sugar. Saccharide is of three types, they are monosaccharide, oligosaccharide and…
Q: Consider the reaction: Fructose-1,6-bisphosphate (F1,6BP) +→ Glyceraldehyde 3-phosphate (GAP) +…
A: All cells require energy in the form of ATP to carry out a variety of functions, such as active…
Q: The visible spectrum of B-carotene (C40oHs, MW 536.89, the orange pigment in carrots) dissolved in…
A: The β- carotene is the orange pigment that causes colouration of the colouration of fruits and…
Q: Looking at the structure of RDV-TP, what changes in the structure of the molecule does the active…
A: The building blocks of DNA and RNA are purine and pyrimidin. Purine are heterocyclic compound.…
Q: In the first step of the aldolase reaction, an active site Lys229 residue, with its side chain amino…
A: Amino acids are organic compounds that consist of an alpha amino group, alpha carboxyl group, and…
Q: Given each set of information which may include common name(s) and the reaction catalyzed, you are…
A: Note : Hi ! Thank you for the question. We are authorized to answer three subparts at a time. Since…
Q: Assume that you have a solution of 0.1 M glucose 6-phosphate. To this solution you add the enzyme…
A: The Phosphoglucomutase is the enzyme that catalyzes the conversion of Glucose 6-Phosphate into…
Q: Phosphoglycerate mutase transfers a phosphoryl group from C3 of 3-phosphoglycerate to C2 position…
A: Phosphoglycerate mutase transfers the phosphate group on C3 of 3-phosphoglycerate to C2, this…
Q: Acid phosphatases are an important group of enzymes that can be detected in human blood serum. Under…
A: 1. Acid phosphatases present in lysosomes of cells and under acidic conditions remove a phosphate…
Q: Draw the structure of alpha-ketoglutarate that is generated in a reaction catalyzed by glutamate…
A: Glutamate dehydrogenase (GDH) catalyzes the conversion of glutamate into α-ketoglutarate. The enzyme…
Q: Given each set of information which may include common name(s) and the reaction catalyzed, you are…
A: Enzymes have a common name that provides little information about the reaction catalyzed by…
Q: An unknown sugar molecule, C12H22O11, is a reducing sugar. It forms an osazone, undergoes…
A: The formula of unknown sugar molecule is C12H22O11. Reducing sugars are those sugar which has free…
Q: Saccharide X occurs in the roots of several species of plants. Deduce the structure of saccharide x…
A: According to the information given in the question Acidic hydrolysis of 1 mole of Stachyose yields…
Q: a The standard free energy (AG,') for the reduction of CoQ by FADH2 (consult Table 20.1) is -61.7…
A: Since we only answer up to 3 sub-parts, we'll answer the first 3 please resubmit the question and…
Q: 2. Glvcolate is oxidized into Glvoxylate by cytochrome Cusing the glycolate oxidase enzyme, The two…
A: Glycolate oxidase is a key enzyme involved in the conversion of glycolate to glyoxylate during…
Q: The isoelectric point (pI) of 6-phosphogluconate dehydrogenase is 6.0. Explain why the buffer used…
A: Enzymes are a class of proteins except for ribozymes (class of RNA) that elevates the pace of the…
Q: Xylose has the same structure as that of glucose except that it has a hydrogen atom at G-5 in place…
A: To answer this question we should have knowledge of Biochemistry.
Q: Sphingosine 1-phosphate (SPP) is important for cell survival. The synthesis of SPP from sphingosine…
A: The Lineweavwe-Burk plot is the plot between 1/[V] vs 1/[S]. Km = -1/ x-intercept Vmax= 1/y…
Q: Chymotrypsin is a digestive enzyme with a catalytic optimum between pH 7.8 and 8.0. However, due to…
A: Henderson-Hasselbalch equation relates pH, pKa and the ratio of concentrations of protonated to…
Q: The enzyme ATCase (Aspartate TransCarbamoylase) catalyzes an early step in the synthesis of the…
A: Enzymes are proteins that play a major role as biochemical catalysts by sppeding up a chemical…
Q: Acid phosphatases are an important group of enzymes that can be detected in human blood serum. Under…
A: 1. Acid phosphatases present in lysosomes of cells and under acidic conditions remove a…
Q: Determine whether the following reactions will be spontaneous under standard biochemical conditions.…
A: An exergonic reaction is one in which the energy level of the products is lower than the energy…
Q: Xanthine oxidase treated with allopurinol results in the formation of a new compound that is an…
A: Xanthine oxidase belongs to the class of oxidoreductase. This enzyme produces reactive oxygen atoms…
Q: Suppose an enzyme needed a cysteine thiol (sulfhydryl) group for its catalytic activity, and…
A: Cysteine is a sulfur-containing amino acid. Cysteine side-chains interact with each other and make…
Q: In order to function as an oxidative phosphorylation uncoupler (page 648), 2,4-dinitrophenol must…
A: Uncouplers such as DNP decreases the formation of high energy phosphate and stimulate oxygen…
Q: The hexapeptide Ala-Met-Leu-Lys-Phe-Asp is digested in the same tube with both Cyanogen Bromide and…
A: Proteins are either charged or neutral. The charge of a peptide/polypeptide chain depends on the…
Q: Galactose 1-phosphate: UDP-glucose uridyltransferase (GALT) is an enzyme important for the…
A: Galactose 1-phosphate: UDP-glucose uridyltransferase (GALT): GALT is an enzyme of the Leloir pathway…
Q: The pKa for histidine is pKa = 6.1 while that for cysteine is pKa = 8.0 2. Assume that both…
A: Histidine and cysteine are catalytic groups present in the given enzyme. The pka for histidine is…
Q: Acid phosphatases are an important group of enzymes that can be detected in human blood serum. Under…
A: Acid phosphatases present in lysosomes of cells and under acidic conditions remove a phosphate group…
Q: Table 4. Rates of saponification at 35°C. Ester k(M-' sec=!) k, relative* (CH,O),PO, (CH,O),P=O…
A: Introduction A phosphodiester bond is formed when two of the hydroxyl groups in phosphoric acid…
Q: Hemp oil contains eicosenoic acid (20:149) as its primary monounsaturated fatty acid. Let's consider…
A: Some of the energy is utilized to generate ATP from ADP and Pi, but ATP is required immediately for…
Q: Enolase catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate + water. The standard…
A: The free energy at nonstandard conditions can be determined using the formula: ΔG = ΔG⁰ + RT ln Q.…
Q: Saccharide X occurs in the roots of several species of plants. Deduce the structure of saccharide x…
A: Stachyose is a tetrasaccharide which consist of 2 α-D-galactose units, 1 α-D-glucose unit and 1…
Q: If 32P labeled (radioactive phosphate) inorganic phosphate were introduced to erythrocytes…
A: Glycolysis converts glucose into pyruvate or lactate with the generation of energy. The process of…
Q: The equilibrium constant Kc for the reaction fructose-1,6-diphosphate ⇋ glyceraldehyde-3-phosphate…
A: Gibbs free energy change (delta G) is a quantitative measure of the favorability of a given reaction…
Triosephosphate isomerase (TIM) catalyzes the conversion of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate. The enzyme’s catalytic groups are Glu 165 and His 95. In the first step of the reaction, these catalytic groups function as a general-base and a general-acid catalyst, respectively. Propose a mechanism for the reaction.
Step by step
Solved in 2 steps
- Choose the CORRECT sequence of glycine formation. transamination of 3-phosphoglycerate → hydrolysis of 3-phosphohydroxypyruvate → hydrolysis of 3-phosphoserine → transfer of the side-chain methylene group of cysteine to tetrahydrofolate → glycine transamination of 3-phosphohydroxypyruvate → oxidation of 3-phosphoglycerate → transfer of the side-chain amino group of serine to tetrahydrofolate → glycine oxidation of 3-phosphoglycerate → oxidation of 3-phosphohydroxypyruvate → hydrolysis of 3-phosphoserine → glycine transamination of 3-phosphohydroxypyruvate → hydrolysis of 3-phosphoserine → oxidation of 3-phosphoglycerate →transfer of the side-chain methylene group of serine to tetrahydrofolate → glycine oxidation of 3-phosphoglycerate → transamination of 3-phosphohydroxypyruvate → hydrolysis of 3-phosphoserine → transfer of the side-chain methylene group of serine to tetrahydrofolate → glycineC Phosphoglycerate enolase coo O H-C-O-P=O CH₂OH 2-Phosphoglycerate This is a (an) d Tyrosine hydroxylase HO coo NH3 L-Tyrosine This is a (an) 0₂ coo C-O-P-C || CH₂ Phosphoenolpyruvate H₂O + HO HO L-DOPA H₂O coo NH3Select the single best answer. What reaction does the enzyme triose phosphate isomerase catalyze? Conversion of dihydroxyacetone phosphate into glyceraldehyde-3-phosphate. Isomerization of 3-phosphoglycerate into 2-phosphoglycerate. Substrate level phosphorylation involving transfer of a phosphoryl group from 1,3-bisphosphoglycerate into 3-phosphoglycerate. Isomerization of glucose-6-phosphate into fructose-6-phosphate.
- In class, I mentioned that fructose is metabolized differently in the liver compared to glucose. Refer to the figure shown below to calculate the number ofATPs you would expect from the metabolism of fructose in the liver. Show your work! Fructokinase Fructose Fructose-1-P АТР ADP Aldolase B Dihydroxy- acetone phosphate Glyceraldehyde АТР Triose kinase Triose phosphate isomerase ADP 4 - Glyceraldehyde-3-P Glycolysis Руruvate Acetyl-CoA Fatty acids and triglyceridesChoose the enzyme and cofactors involved in the reaction of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis. H H-TOPO Fo HOTH HDH HOH MOTOPOP K E H-TOH H OPO Problem 3 of 17 A B Q D E fructose-1,6-bisphosphatase phosphoglucose isomerase glucose-6-phosphatase phosphoglycerate kinase hexokinaseBased on the image below, select the correct statements. Note: There may be more than 1 correct response. Ribose 5-phosphate ribose phosphate pyrophosphokinase (PRPP synthetase) glutamine-PRPP amidotransferase adenylosuccinate synthetase AMP -> PRPP 5-Phosphoribosylamine I adenylosuccinate lyase 9 steps Adenylosuccinate AMP IMP <-- ADP <- AMP <-- GMP <-- IMP IMP dehydrogenase <- GMP. XMP ADP ATP XMP-glutamine amidotransferase GMP يا Increased levels of ADP inhibit the production of PRPP. Increased levels of GMP inhibit the production of XMP. Increased ADP activates PRPP synthase to increase PRPP levels. Increased IMP activates glutamine-PRPP amidotransferase to further increase IMP levels.
- Which of the structures below is that of О-а-D-glucopyranosy-(1->1)- а-D-glucoругanoside CH2OH CH2OH O. H H. он H. он H OH ÓH CH2OH HOH2 H. CH2OH CH2OH O. H H. он он H OH он CH2OH H. о, он он H он онHandwritten Identify the molecule names, enzyme name, enzyme classification and change in reaction(for glycolysis pathway)Describe the gluconeogenesis. What are the substrates for gluconeogenesis? (yellow boxes) and write the names of the enzymes belong to the gluconeogenic pathway. Glucose 4 se-6-phosphate usphoglucose isomerase Fructose-6-phosphate Fructose-1,6-bisphosphate HAidolase Triose phosphate Dihydroxyacetone phosphate isomerase Glyceraldehyde 3-phosphate P.. NAD CH,OH Glyceraldehyde 3-phosphate dehydrogenase 1,3-Bisphosphoglycerate CH,OPO,- NADH ADP Phosphoglycerate kinase ATP 3-Phosphoglycerate Phosphoglycerate || mutase 2-Phosphoglycerate 2 X Enolase Phosphoenolpyruvate GDP, CO, GIP Oxaloacetate ADP + P, 1 ATP, HCOS Pyruvate
- Lactose is made up of D-galactose and one unit of D-glucose joined by a alpa-1,4-glycosidic bond and can be hydrolyzed by the enzyme lactase True FalsePhosphoribosyltransferase (PRT) catalyzes the attachment of a salvaged purine nitrogenous base on the activated form of ribose-5-phosphate called 5-phosphoribosyl- α α-pyrophosphate ( α α-PRPP). True Or FalseWhich of the following statements is not true about the catalytic triad in chymotrypsin? Group of answer choices the side chain of the serine 195 is hydrogen bonded to the imidazole ring of histidine the -NH group of the imidazole ring of histidine is hydrogen bonded to the carboxylate group of aspartate 102 the histidine residue serves to position the aspartate 102 side chain and to polarize its carboxylate group so that it is poised for deprotonation histidine acts as a general base catalyst none of these