In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. CH₂MgBr CH3O NO Edit Imine Ion Intermediate P

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter11: Ethers, Epoxides, And Sulfides
Section: Chapter Questions
Problem 11.42P
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In the reaction of a nitrile with a Grignard reagent, there are two
steps: a) nucleophilic addition of the Grignard to form an imine
ion and b) hydrolysis of the imine to form a ketone.
Draw the intermediate and the final product in this reaction.
Ignore inorganic byproducts.
N
CH3MgBr
CH3O
NO
Edit Imine Ion Intermediate
1. H₂O*
Q
Problem 25 c
Transcribed Image Text:In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. N CH3MgBr CH3O NO Edit Imine Ion Intermediate 1. H₂O* Q Problem 25 c
NO
Edit Imine Ion Intermediate
CH3O
CH3O
1. H3O+
2. Neutralizing work-up
Edit Final Product
Transcribed Image Text:NO Edit Imine Ion Intermediate CH3O CH3O 1. H3O+ 2. Neutralizing work-up Edit Final Product
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