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In the absence of the drug, Xor's blood pressure would drop as low as 70 mmHg. As the blood pressure falls to 70 mm Hg, how much drug should we administer to restore the blood pressure to 105 mmH? To answer this question, assume the following conditions: 1. the drug directly affects the rate of blood flow from the heart (L/min), 2. the drug has no effect at dosages below 41 g and has a linear effect on the rate of blood flow at dosages above 41 g. The slope of this linear effect is 2.91 (L/min) / g of drug, and 3. the drug must increase the rate of blood flow enough to increase the blood pressure from 70 mm Hg to 105 mmHg, and 4. the slope of the linear relationship between the rate of blood flow from the heart and the blood pressure in megaraffes is 0.225 mmHg/(L/min). Our goal is to determine the dosage of the drug needed to increase the blood pressure by 35 mmHg. We'll work backwards from this goal to determine the correct dose.

In the absence of the drug, Xor's blood pressure would drop as low as 70 mmHg. As the blood pressure falls to 70 mm Hg, how much drug should we administer to restore the blood pressure to 105 mmH? To answer this question, assume the following conditions: 1. the drug directly affects the rate of blood flow from the heart (L/min), 2. the drug has no effect at dosages below 41 g and has a linear effect on the rate of blood flow at dosages above 41 g. The slope of this linear effect is 2.91 (L/min) / g of drug, and 3. the drug must increase the rate of blood flow enough to increase the blood pressure from 70 mm Hg to 105 mmHg, and 4. the slope of the linear relationship between the rate of blood flow from the heart and the blood pressure in megaraffes is 0.225 mmHg/(L/min). Our goal is to determine the dosage of the drug needed to increase the blood pressure by 35 mmHg. We'll work backwards from this goal to determine the correct dose.

Biomedical Instrumentation Systems
Biomedical Instrumentation Systems
1st Edition
ISBN:9781133478294
Author:Chatterjee
Publisher:Chatterjee
Chapter9: Instrumentation In Blood Circulation
Section: Chapter Questions
Problem 4P
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F2 over the arrow connecting these variables. The slope of this relationship is 0.225 mmHg/(L/min). In the absence of the drug, Xor's blood pressure would drop as low as 70 mmHg. As the blood pressure falls to 70 mm Hg, how much drug should we administer to restore the blood pressure to 105 mmH? To answer this question, assume the following conditions: 1. the drug directly affects the rate of blood flow from the heart (L/min), 2. the drug has no effect at dosages below 41 g and has a linear effect on the rate of blood flow at dosages above 41 g. The slope of this linear effect is 2.91 (L/min) / g of drug, and 3. the drug must increase the rate of blood flow enough to increase the blood pressure from 70 mm Hg to 105 mmHg, and 4. the slope of the linear relationship between the rate of blood flow from the heart and the blood pressure in megaraffes is 0.225 mmHg/(L/min). Our goal is to determine the dosage of the drug needed to increase the blood pressure by 35 mmHg. We'll work backwards from this goal to determine the correct dose. Directions: Use the path model and slopes in Figure 12 to answer questions 28-29. 28. How much does the rate of blood flow from the heart (L/min) need to increase to cause the blood pressure to increase by 35 mmHg? Round all calculated values to the nearest whole number. For example, if you calculate the value as 3.8218, round to 4. Amount to increase the rate of blood flow from the heart (L/min) = 29. What dosage of the drug (g) must we administer to change the rate of blood flow from the heart (L/min) by the amount that you indicated in your answer to the previous question? Round all calculated values to the nearest whole number. For example, if you calculate the value as 3.8218, round to 4. Hint: Remember that the drug has no effect on the rate of blood flow at dosages of 41 g or less, so be sure to add 41 g to your final answer no matter what. Dosage of drug (g) = 80 F3 Q F4 F5 DII
Transcribed Image Text:F2 over the arrow connecting these variables. The slope of this relationship is 0.225 mmHg/(L/min). In the absence of the drug, Xor's blood pressure would drop as low as 70 mmHg. As the blood pressure falls to 70 mm Hg, how much drug should we administer to restore the blood pressure to 105 mmH? To answer this question, assume the following conditions: 1. the drug directly affects the rate of blood flow from the heart (L/min), 2. the drug has no effect at dosages below 41 g and has a linear effect on the rate of blood flow at dosages above 41 g. The slope of this linear effect is 2.91 (L/min) / g of drug, and 3. the drug must increase the rate of blood flow enough to increase the blood pressure from 70 mm Hg to 105 mmHg, and 4. the slope of the linear relationship between the rate of blood flow from the heart and the blood pressure in megaraffes is 0.225 mmHg/(L/min). Our goal is to determine the dosage of the drug needed to increase the blood pressure by 35 mmHg. We'll work backwards from this goal to determine the correct dose. Directions: Use the path model and slopes in Figure 12 to answer questions 28-29. 28. How much does the rate of blood flow from the heart (L/min) need to increase to cause the blood pressure to increase by 35 mmHg? Round all calculated values to the nearest whole number. For example, if you calculate the value as 3.8218, round to 4. Amount to increase the rate of blood flow from the heart (L/min) = 29. What dosage of the drug (g) must we administer to change the rate of blood flow from the heart (L/min) by the amount that you indicated in your answer to the previous question? Round all calculated values to the nearest whole number. For example, if you calculate the value as 3.8218, round to 4. Hint: Remember that the drug has no effect on the rate of blood flow at dosages of 41 g or less, so be sure to add 41 g to your final answer no matter what. Dosage of drug (g) = 80 F3 Q F4 F5 DII
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