In biochemical reactions, decarboxylation of carboxylic acids typically takes place for-keto carboxylic acids. Justify a rational why nature opted for-keto carboxylic acid decarboxylation. Among the following types of biochemical reactions, ester hydrolysis, rearrangement reactions, water elimination reactions, and anhydride hydrolyses, which one is the most favorable one. Rank the above reactions types in the order of being the most to least favorable reaction

In biochemical reactions, decarboxylation of carboxylic acids typically takes place for-keto carboxylic acids. Justify a rational why nature opted for-keto carboxylic acid decarboxylation. Among the following types of biochemical reactions, ester hydrolysis, rearrangement reactions, water elimination reactions, and anhydride hydrolyses, which one is the most favorable one. Rank the above reactions types in the order of being the most to least favorable reaction

Chemistry: Principles and Reactions

8th Edition

ISBN:9781305079373

Author:William L. Masterton, Cecile N. Hurley

Publisher:William L. Masterton, Cecile N. Hurley

Chapter22: Organic Chemistry

Section: Chapter Questions

Problem 28QAP: When the conjugate acid of aniline, C6H5NH3+, reacts with the acetate ion, the following reaction...

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When the conjugate acid of aniline, C6H5NH3+, reacts with the acetate ion, the following reaction takes place: C6H5NH3+(aq)+CH3COO(aq)C6H5NH2(aq)+CH3COOH(aq) If Kafor C6H5NH3+ is 1.35105 and Kafor CH3COOH is 1.86105 , what is K for the reaction?
Carboxylic Acid Derivatives Resolve the reactions.
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Two methods convert an alkyl halide into a carboxylic acid having one more carbon atom. (1] R-X + "CN R-CN R,COOH COOH (Section 22.18) + X- new C-C bond [1] CO2 RCOOH (Section 20.14) [2] H3O [2] R-X + Mg R-MgX Depending on the structure of the alkyl halide, one or both of these methods may be employed. For each alkyl halide, write out a stepwise sequence that converts it to a carboxylic acid with one more carbon atom. If both methods work, draw both routes. If one method cannot be used, state why it can't. Br a. CH,CI b. c. (CH3)3CCI d. HOCH,CH,CH,CH,Br
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The Brønsted-Lowry definition of acids and bases is: Acids are proton donors, bases are proton acceptors Acids are nucleophiles and bases are electrophiles Acids are proton acceptors, bases are proton donors Carboxy groups are acids and amine groups are bases Carboxy groups are electrophiles and amine groups are nucelophiles
H NH₂ ཡིནྣཾ ༥ ཨ ཨནྡྷ༥ ༠ ཨི་ཝཱ, ཙ ཨ་ར༩ H NH3+ the acidity of the amine ion drives the reaction to shift toward the conjugate base of the carboxylic acid product. the resulting carboxylic acid ion is a weaker base than an acetate ion. O aldehydes are more reactive toward nucleophiles than ketones. Onucleophilic attack occurs preferentially at the less hindered carbon of the formyl group.
Consider the following reaction between an alkyl halide and a weak base. & I + CH₂OH