Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter16: Human Genetics And The Human Genome
Section16.3: Genetic Diseases Caused By Single-gene Mutations
Problem 7LO: State whether each of the following genetic defects is inherited as an autosomal recessive,...
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Fill in ALL the charts AND answer every question/fill in the blank. Make sure it is ALL accurate and complete.
Transcribed Image Text:Autosomal Recessive Disorder: Cystic Fibrosis
2. Cystic fibrosis is lethal autosomal recessive disorder in humans. It is the most common fatal
disorder in the United States. Its hallmark is bacterial infections of the lungs and intestine. A
woman who is a carrier of cystic fibrosis (Cc) has children with a man who is also a carrier
(Cc). What are the chances that a particular child will have cystic fibrosis? What are the
chances that a particular child will be a carrier?
a. Phenotypes of the parents:
b. Genotypes of the parents:
c. Gamete genotypes:
d. Punnett Square:
(egg)
Mother:
Mother:
Egg :
(sperm)
Father:
Father:
Sperm :
e. List all possible genotypes of offspring of these parents:
1. Which of these genotypes are heterozygous?
2. Which of these genotypes are homozygous?
f. List all the possible phenotypes of offspring of these parents:
g. Calculate the probability of each genotype and phenotype as listed. Fill in table on the
following page.
Transcribed Image Text:Table 3: Expected Probabilities for Cystic Fibrosis
Genotype Genotype
Genotype
probability as a
percent
CC
Cc
сс
CC
Cc
probability as a
fraction
i.
сс
Table 4. Data for Cystic Fibrosis
Genotype Total #
(Total #
h. What are the chances a child will have cystic fibrosis?
Report data as a percentage:
as a fraction:
We are going to test the ratio of offspring given the parental genotypes above for Cystic Fibrosis
by using a coin toss. Obtain the appropriate coins for the mother and father. Follow the previous
coin toss procedure.
Phenotype
What are the chances a child will be a carrier of cystic fibrosis?
Report data as a percentage:
as a fraction:
Phenotype
probability as a
fraction
genotype
after 24
tosses
genotype
/24) x
100
in %
Phenotype
probability as
a percent
Probability Phenotype Total #
from
Punnett
Square in
%
phenotype
after 24
tosses
(total #
phenotype
/24) X
100
in %
Probability
from
Punnett
Square in
%
Did your results from the coin tosses support your prediction from the Punnett Square? Specify
the data you used.
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