c) Draw a detailed mechanism, showing the movement of all relevant electrons, of the enzymatic reduction of the ketone (1) by an enzyme using NADH as a cofactor to produce a secondary alcohol. Assume the enzyme active site provides any acidic or basic amino acid sidechains required. You can use the truncated structure of NADH for your answer to this question. € R₂ R₁ NH₂ Truncated structure of NADH
c) Draw a detailed mechanism, showing the movement of all relevant electrons, of the enzymatic reduction of the ketone (1) by an enzyme using NADH as a cofactor to produce a secondary alcohol. Assume the enzyme active site provides any acidic or basic amino acid sidechains required. You can use the truncated structure of NADH for your answer to this question. € R₂ R₁ NH₂ Truncated structure of NADH
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter18: Functional Derivatives Of Carboxylic Acids
Section18.8: Interconversion Of Functional Derivatives
Problem BQ: Several compounds have been found to inhibit -lactamase, and drugs based on these compounds can be...
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