Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations.

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter6: Oral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 6.6P
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  1. Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations.
  2. The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers.
  3. How the cracking is occurring in the emulsions?
  4. If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena.
  5. Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examples
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According to the guidelines we have to answer the first question please try to post the questions separately.

Physical properties of the active pharmaceutical ingredient and the excipients used to make the formulation are very important. There are many other points we need to consider before making the formulation which is used for the administration of the patient.

 

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