Below is a set of sequence reads from an individual aligned to a reference sequence. AGACACTCCACC CGATCAGAATCG GATCATCATCGA CGACCTGAAAAG CGAATATGCTGG ACACTCCACCTG ATCAGAATCGAA ТСАТСАТСGАСТ ACCTGAAAAGAT AATATGATGGTA AG ACTCCACCTGCCAT GAATCGAAGA ATCATCGACTCG CTGAAAAGATCG TATGATGGTAA AGAC ТССАССТGCСАТСА ATCGAAGATC CATCGACTCGAC GAAAAGATCGAA TV GTAA AGACAC САССTGCGAТСAGA CGAAGATCAT TCGACTCGACСТ AAAGATCGA CTGGTAA AGACACTC CCTGCGATCAGAAT AAGATCATCА GACTCGACCTGA AGATCGAATATG GGTAA AGACACTCCA TGCCATCAGAATCG GATCATCATC СТCGACСTGAA ATCGAATATGAT TAA AGACACTCGACCTGCCATCAGAATCGAAGATCATCATCGACTCGACCTGAAAAGATCGAATATGATGGTAA Looking at the alignment what are the number of the following? Homozygous SNPS Heterozygous SNPS Homozygous Insertions Heterozygous Insertions Homozygous Deletions Heterozygous Deletions

Q: Which of the following sequences is most likely to be recognized and cut by a 6- cutter restriction…

A: Restriction enzyme is an enzyme that cuts DNA into small fragments at specific sites within…

Q: If you design a set of primers for a PCR reaction, please describe the temperature that you will set…

A: PCR This is Polymerase Chain Reaction. This technique is used to amplify the specific sequences of…

Q: Devonte asked his colleague George to verify his results by repeating the sequencing experiment in a…

A: Sanger dideoxy sequencing method is also known in the genetics as chain-termination sequencing this…

Q: Which of the following pairs of sequences would be considered different alleles in DNA profiling?…

A: DNA profiling employs highly variable conserved regions known as variable number tandem repeats…

Q: Identify the type of mutation that occurred to produce the abnormal hemoglobin. Explain why you…

A: Nonsense mutation: This is a condition in which a protein loses its function, resulting in sickness…

Q: This BLAST program performs the greatest number of searches for the same query sequence and database…

A: BLAST is used in bioinformatics an an algorithm which compares the sequences of amino acids and of…

Q: Given below is the DNA template. What are the gene products? 3’ TACCGGCCTATCTAGGGCCATGGCTTAATTCCC 5’…

A: DNA is the sequence of Nucleotides that are transcribed into mRNA during transcription. Once DNA is…

Q: ACAACCCCAAGCCTTC

A: Answer : PROBE - DNA probes are the short stretches of single stranded DNA used to detect the…

Q: 6. Refer to the figure answer the following questions. CLUSTAL W (1.83) multiple sequence alignment…

A: DNA is the genetic material for many multicellular organisms. The DNA present in all organisms is…

Q: You grow this weird looking organism in lab and have no idea what it is. You decide to sequence its…

A: As organisms evolve, their DNA and protein sequences change. According to the molecular clock…

Q: With regards to this sequence below please answer this quistions 1) What is the format of the…

A: answer given below

Q: Design 6 bp primers to amplify the region of this sequence that is highlighted in yellow. 1…

A: Primers:  Short nucleotide sequences usually 6-10 bp in size that acts as the initiation point for…

Q: Which forward are reverse primers will amplify the following sequence by PCR?…

A: As given in the question, forward and reverse primer sequences are to be identified to amplify the…

Q: Hide Colors View Alignment File CLUSTAL W (1.83) multiple sequence alignment Oyster AA Corn_AA…

A: Amino acid sequences of proteins from different organisms can be compared using bioinformatic tools…

Q: A. The insertion shifts the reading frame to the right .The deletion frameshifts the reading frame…

A: *NOTE: Kindly repost for other questions Dear Student as per the guidelines we are supposed to…

Q: What does BLAST stand for? Basic Local Alignment Search Tool Basic Local Alignment SequenceToo Best…

A: The best option is (a) Basic Local Alignment Search Tool.

Q: Obtain the self-dotplot of the following sequence to identify repeat region:…

A: There are various alignment tools available at EMBOSS. It is studied under the domain of…

Q: Complete the DNA and RNA sequencing for the translation and creation of proteins. 1. DNA  3' CCC…

A: The genomic structure of an organism consists of DNA which contains sugar molecule, phosphate group,…

Q: The figure below depicts the start of the CDNA sequence of the gene AGAMOUS from the model plant…

A: Central dogma was proposed by Francis Crick. The RNA is formed from DNA with the help of enzyme RNA…

Q: Based on the restriction enzyme specificities given below, what was the enzyme utilized to produce…

A: The corner stone of genetic engineering or recombinant DNA technology is a special class of enzymes…

Q: be used for a restriction fragment length polymorphism (RFLP) diagnostic assay to identify…

A: Polymerase chain reaction, or  as we say PCR, is a technique used to make many copies of a specific…

Q: CDNA libraries Select an answer and submit. For keyboard navigation, use the select an answer. a a)…

A: Gene is the primary fundamental unit. These are made up of Deoxyribonucleic acid (DNA). The DNAs…

Q: -35 sequence Pribnow box 5' GATTCCGTATTACAGCATAGGCTATATTCACGTGGTACGCTA 3' 3'…

A:

Q: Using the GeneEx Computer Simulation http://intro.bio.umb.edu/MOOC/jsGX/JsGenex_C2.html Complete the…

A: A gene consists of : Promoter, exons and introns. In the question, we have to create a hypothetical…

Q: Identify the mRNA sequence that encodes the protein Design primers that will allow them to amplify…

A: Deoxyribonucleic acid(DNA) is a molecule comprised of two polynucleotide chains coiled around each…

Q: What is the sequence of the sample DNA submitted for sequencing given the gel electrophoresis…

A: Sanger sequencing method is chain terminating method.

Q: Horizontal sequence :RIVL Vertical sequence:FMK   Scoring rules: g/o = -3, g/e = -1, match or…

A: Substitution matrix are of two types called BLOSUM and PAM.  Both these Substitution  matrices are…

Q: Which of the following is most likely to be a restriction enzyme recognition sequence? O AAAAAA O…

A: A palindromic sequence is a sequence of nucleic acids within double helix of DNA and / or RNA that…

Q: Method on the following 5 sequences and find the best multiple sequence alignments. Sequence # 1:…

A: Progressive alignment  is a heuristic for multiple sequence alignment that does not optimize any…

Q: SspI --- 5' AAT - ATT 3' 5' GGATAATATT GTTAACAATCTCTACGGGTTAACACCCTTGGAATATTTTAA 3' 3'…

A: DNA is one of the two nucleic acids made up of monomer units of nucleotides. DNA nucleotides are…

Q: Draw the structure of a typical insertion sequence and identify its parts.

A: There are two types of transposons such as replicative and non-replicative transposons. They are…

Q: TGAGGATGAAACTCACACCGGGGCGCAGTTTGGCACTTAGATTCTTGTACACGACCTAGTATAACACAGTT Compare this mutated sense…

A: ORIGINAL:- TGAGGATGAAACTCACACCGGGGCGCAAGTTTGGCACTTAGATTCTTGGCACTTAGATTCTTGTACACGACCTAGTATAACACAGTT…

Q: The following DNA sequences were used to generate a contig from a genome sequencing project.…

A: Sequencing It is a method through which the complete genetic makeup of the organism is identified.…

Q: The following bacterial DNA genome is composed of three sequences: TGGCGGT / ACGTTAC / GGATAGG Using…

A: Clustered regularly interspaced short palindromic repeats or CRISPR is a family of nucleotide…

Q: Transcribe the following DNA sequence from HbS. Record your answer to submit for grading. DNA…

A: DNA Transcription: it is the process of making an RNA copy of a DNA  sequence. It is the first step…

Q: You are asked to design PCR primers (18 nucleotides) to amplify the coding region (without the stop…

A: If you cloned your DNA of interest between the BamHI and EcoRI sites, you could sequence using the…

Q: Table I CAC GTA GACTGAGG ACTC CACGTA GACTGAGG ACAC Wild-type beta-globin gene fragment Sickle-cell…

A: Abrupt changes in the DNA sequence of nucleotides is called mutation. Even a single nucleotide…

Q: Write the sequences of the two 12-residue primers that could be used to amplify the following DNA…

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: design a molecular beacon probe (15-20 NT long) for qPCR of the gene   5`-…

A: PCR is a technique used in molecular studies to amplify a gene. PCR is an abbreviation for a…

Q: You have the following sequence reads from a genomic clone of the Homo sapiens genome: Read 1:…

A: The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA in the 23…

Q: TRANSCRIBE this DNA sequence: TACGTTACT O AUGCAAUGA OATGCAATGA AUGGATUGA TACGTTACT

A: Hi, thank you for posting the question on Bartleby. As per the guidelines, we can answer only one…

Q: What is the symbol on the first line of a raw read that tells you a unique sequence follows?

A: Bioinformatics is an interdisciplinary field of study which has diverse application in the field…

Q: 3. Examine the following DNA sequence and determine wh type of mutation, if any, produced the…

A: A heritable genetic change in the genetic material of an organism that gives rise to alternate…

Q: To achieve a 10x depth coverage for a genome of length 10 Mbp, how many reads of 100 bp are…

A: A Coverage is multiplier based on  total size of the genome. Formula =  Coverage = (read length) x…

Q: Sequence: CCACCTGTACCCGGACACACCCTGGTGTCC   What human disease has been connected to this gene?…

A: The given sequence  CCACCTGTACCCGGACACACCCTGGTGTCC is a protein sequence that encodes the protein…

Q: Given the electrophoresis profile of a Sanger sequencing result, what was the sequence of the…

A: The Sanger sequencing method is also called as chain termination method. In this method, dideoxy…

Q: advantages of using larger restriction fragments when constructing a genomic library of human DNA

A: DNA library A DNA library is a collection of cloned DNA fragments containing the gene of interest.…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.