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a) Mention the TNM classification of Cancer.?
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- Explain Three mechanisms for viral induction of cancer.Select all of the sentences below that correctly describe the role of a healthy diet and lifestyle in cancer risk and progression. Select all that apply. A)Dietary supplements are definitively linked to lowering cancer risk. B)Consumption of processed meat containing nitrates and nitrites may increase a person’s risk of certain cancers. C)Grilling is a healthy cooking method; therefore, the consumption of all types of grilled meat will help reduce the risk of cancer. D)Folate may help reduce the incidence of colon cancer. E)Fruits and vegetables contain phytochemicals, antioxidants, and dietary fiber, all of which help reduce the risk of certain cancers.1)Briefly describe three chemical factors affecting cell division. 2)Briefly describe the three classifications of cancer based on origin.
- What may account for the increased incidence of cancer among elderly people?Explain several ways by which the treatment of cancer by chemotherapy may temporarily create additional health problems for the patient.1. Describe & explain the pathophysiology of cancer based on the diagram. Reference: https://www.onlinebiologynotes.com/cancer-etiology-pathophysiology-types-diagnosis-and- treatment/ Acquired (environmental) DNA damaging agents: • chemical • radiation viruses Activation of growth- promoting oncogenes NORMAL CELL DNA Damage Failure of DNA repair Mutations in the genome of somatic cells Alteration of genes that regulate apoptosis Malignant neoplasm / Successful DNA repair CANCER Inherited mutations: • Genes affecting DNA repair • Genes affecting cell growth Expression of altered gene products and loss of regulatory gene products Inactivation of cancer suppresor genes Clonal expansion Additional mutations (progression) T Heterogeneity
- -Describe the seven hallmarks of cancer i) List the seven hallmarks ii) Connect each hallmark to the type of change -Explain importance of p53 i) Know the function of p53 ii) Explain how loss of p53 can result in several hallmarks of cancerList five reasons that make lipoma a benign tumourResearch studies that have been conducted about breast cancer risk have found that 60% of breast cancer cases are due to genetic risk factors. This is a measure of" a) Risk b) Odds c) Attributable risk percent d) Incidence rate
