A device consisting of microtubes (radius 30 um and length of 0.3 cm) is line on its inside with a monolayer of cells producing a compound of interest. z It is essential for the CO2 produced by these cells to be adequately removed. The cells on the inside of the microtubes R cell monolayer produce CO2 at a rate of 3.4 x 10-9 The perfusion medium (equivalent to saline at 37°C) entering the tube is essentially free of CO2, where the diffusion coefficient of CO2 in the medium is 2 x 10-5 9 g/s.

Principles of Heat Transfer (Activate Learning with these NEW titles from Engineering!)
8th Edition
ISBN:9781305387102
Author:Kreith, Frank; Manglik, Raj M.
Publisher:Kreith, Frank; Manglik, Raj M.
Chapter3: Transient Heat Conduction
Section: Chapter Questions
Problem 3.21P
icon
Related questions
Question

6

A device consisting of microtubes (radius 30
um and length of 0.3 cm) is line on its inside
with a monolayer of cells producing a
compound of interest.
z It is essential for the CO2 produced by
L
R
cell monolayer
these cells to be adequately removed.
The cells on the inside of the microtubes
produce CO2 at a rate of 3.4 x 10-9 g/s.
The perfusion medium (equivalent to saline at 37°C) entering the tube is essentially
free of CO2, where the diffusion coefficient of CO2 in the medium is 2 x 10-5
cm2/s.
If the maximum level of CO2 to which any cell is exposed must be less than 1 x 10-4
g/ml:
1) What is the concentration (in g/cm3) leaving the tube,
2) What is the minimum flow rate (in uL/min) must pass through each tube,
3) Determine if the axial diffusion can be neglected?
Transcribed Image Text:A device consisting of microtubes (radius 30 um and length of 0.3 cm) is line on its inside with a monolayer of cells producing a compound of interest. z It is essential for the CO2 produced by L R cell monolayer these cells to be adequately removed. The cells on the inside of the microtubes produce CO2 at a rate of 3.4 x 10-9 g/s. The perfusion medium (equivalent to saline at 37°C) entering the tube is essentially free of CO2, where the diffusion coefficient of CO2 in the medium is 2 x 10-5 cm2/s. If the maximum level of CO2 to which any cell is exposed must be less than 1 x 10-4 g/ml: 1) What is the concentration (in g/cm3) leaving the tube, 2) What is the minimum flow rate (in uL/min) must pass through each tube, 3) Determine if the axial diffusion can be neglected?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Basic Mechanics Problems
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, mechanical-engineering and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Principles of Heat Transfer (Activate Learning wi…
Principles of Heat Transfer (Activate Learning wi…
Mechanical Engineering
ISBN:
9781305387102
Author:
Kreith, Frank; Manglik, Raj M.
Publisher:
Cengage Learning