A breeder comes to you with a female cat (Fifi) affected with a disease. This cat has an affected male sibling and 2 unaffected littermates. Their dam (mother) is normal, but Fifi’s maternal granddam is affected with the disease. Their sire (father) is normal, but Fifi’s paternal grandsire is affected. The breeder wants to mate Fifi to a normal male. This male has 2 female littermates, one that is affected with the disease and the other normal. The male’s dam is also affected with the disease but the status of the male’s sire is unknown because he is dead a. Draw the pedigree using correct symbols, affected individuals and numbering the generations and individuals in the pedigree. b. What is the probability that the mating of Fifi with the described male will produce a kitten affected with the disease?
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A breeder comes to you with a female cat (Fifi) affected with a disease. This cat has an affected male sibling and 2 unaffected littermates. Their dam (mother) is normal, but Fifi’s maternal granddam is affected with the disease. Their sire (father) is normal, but Fifi’s paternal grandsire is affected. The breeder wants to mate Fifi to a normal male. This male has 2 female littermates, one that is affected with the disease and the other normal. The male’s dam is also affected with the disease but the status of the male’s sire is unknown because he is dead
a. Draw the pedigree using correct symbols, affected individuals and numbering the generations and individuals in the pedigree.
b. What is the probability that the mating of Fifi with the described male will produce a kitten affected with the disease?
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