5Worksheet: Chirality - Handedness of Molecules1Label the chirality center/stereocenter in the given molecules using an asterisk. The compounds contain zero or onechirality center.Ha. CH3CHCH2CH3b. (CH3)3CHC. CH2=CHCHCH3d.C-CH3OHBr2Label the chirality center in each drug.346a. BrHb.CH2CH2N(CH3)2brompheniramine(antihistamine)CH2CH2NHCH3fluoxetineTrade name: Prozac(antidepressant)-CF3Mark each stereocenter in these molecules with an asterisk. Note that not all contain stereocenters.OHOHHOOHHOb.a.OHOHLocate the chirality center: (a) fluoxetine, an antidepressant; (b) sertraline, the generic name for the antidepressant Zoloft.CH2CH2NHCH3fluoxetineTrade name: Prozac(antidepressant)-CF3CH3NH-Label the chirality center in each compound and draw both enantiomers.a. CH3CHCH2CH3b. CH3CH2CHCH2OHOHsertralinePropranolol (trade name: Inderal) is used in the treatment of high blood pressure and heart disease.(a) Locate the chirality center in propranolol. (b) Draw both enantiomers of propranolol.OCH2CHCH2NHCH(CH3)2онpropranolol

Chiral Centre is that centre which have all the different groups around it.In case of carbon, if all…

Answered: 5 Worksheet: Chirality - Handedness of…

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter12: Chirality

Section: Chapter Questions

Problem 19E

See similar textbooks

Similar questions

8. Which of the following descriptions provided is an accurate description of the given molecule below CH2CH3 H. CH3 CH2 H: °CH3 CH2CH3 А. Has two chirality centers and a plane of symmetry, therefore it is achiral В. Has two chirality center, therefore it is chiral С. Has two chirality centers and a plane of symmetry, therefore it is chiral. D. Has two chirality centers and no plane of symmetry, therefore it is achiral
How many chirality center/s are in this molecule? OH H3C-CH,CHCH,CH3 OA. The molecule has not chirality center OB 1 OC2 OD 3
Specify whether the configuration of the chirality center in the structure is R or S. (Other terms used for chirality center include chiral center, stereocenter, and stereogenic center.) CI H 国 ball & stick v +| labels -
5. Identify the chirality center as R- or S- HN OH __)-pindolol beta-blocker (5-HT antagonist) a. Constitutional isomers b. Stereoisomers _)-nicotine binds to nicotinic acetylcholine receptors i. Enantiomers ii. Diastereomers Ph Ph 6a. Draw 1-ethyl-3-iodocyclohexane in all possible R/S ways (RR, SS, RS, SR). 6b. Of this set (4 molecules), which are A. Isomers C _)-methadone an opioid use to treat addiction to other opioidss. What? (opioid agonist)
1. Locate/Label the chirality center of the given molecules. a. OH H2N C H CH3 CH3 SH b. OH HO CH2NHC(CH3)3 HOCH2
Part B. Mark each chirality center in each molecule with an asterisk (*). Name Biotin Colchicine HN H- H3C S Structure ΝΗ H H3C HN CH3 OH CH3 O-CH3 Comment a nutrient essential for growth 3 chiral centers used in biology research to induce doubling of chromosomes 1 chiral centers
4G 08:48 How many chirality centers are present in the compound shown? Cl CI OA1 OB. 3 OC The compound does not have a chirality carbon and therefore is achiral O02 Add a caption... > Status (Custom)
Ans: 2. Assign the absolute configuration of the chirality center as R or S. O HO- Ans: Assign the absolute configuration of the chirality center as R or S. Ans: OH 3. Drawn below is the structure of Crestor® (rosuvastatin), a medication used to reduce cholesterol. Assign the absolute configurations of the two chirality centers as R or S. | NH 4. What is the relationship of the following two structures? OH OHI NH OH OH A. Enantiomers B. Diastereomers. C. Constitutional isomers D. Identical Ans: NH CO₂H 5. What is the relationship of the following two structures? OH OH A. Enantiomers B. Diastereomers C. Constitutional isomers D. Identical Ans: Loo HO OH 6. What is the relationship of the following two structures? HO HO \,.. ...NH محمد HO OH eilte neu-1071 Mamos a diartwollen preto a
Ans: Assign the absolute configuration of the chirality center as R or S. 2. Assign the absolute configuration of the chirality center as R or S. HO- Ans: OH
OCH3 HN- N. N. СООН Moxifloxacin Indicate the orientation around each of the labeled chirality centers in moxifloxacin. If there are only two chirality centers in the molecule choose none for the Center c.
Indicate which atoms in the following compound are chiral centers. H3C. HO a H3C CH2 (Provide a list of letters without spacing. Alphabetize your list (abcd).) Chiral centers: How many stereoisomers do you expect for this compound?
Identify the absolute configuration of the chirality centers in each of the following compounds as R or S. Note: if multiple chirality centers are present, indicate the stereochemical designations as: RR, SS, RS, or SR. (Other terms used for chirality center include chiral center, stereocenter, and stereogenic center.) Co,H OH CO2H D. H H2N H HO2C OH CO,H HO CO2H b.) a.) d.) CO,H H H2N CO2H f) HO g.) h.)

SEE MORE QUESTIONS

Recommended textbooks for you

Organic Chemistry: A Guided Inquiry

Chemistry

ISBN:

9780618974122

Author:

Andrei Straumanis

Publisher:

Cengage Learning

Organic Chemistry: A Guided Inquiry

Chemistry

ISBN:

9780618974122

Author:

Andrei Straumanis

Publisher:

Cengage Learning

SEE MORE TEXTBOOKS