2. In the previous example, formaldehyde has been used for the synthesis of the corresponding pyridine. Identify the aldehydes used in the synthesis of the following pyridines: NO2 EtO OEt EtO OEt EtO OEt H3C CH3 H3C CH3 H3C CH3 1 2 3 3. Using curved arrows, draw the mechanism of the Pinner synthesis of pyrimidine (3): CH3 CH3 HCI NH2 H3C HN CH3 H;C CH3 1

2. In the previous example, formaldehyde has been used for the synthesis of the corresponding pyridine. Identify the aldehydes used in the synthesis of the following pyridines: NO2 EtO OEt EtO OEt EtO OEt H3C CH3 H3C CH3 H3C CH3 1 2 3 3. Using curved arrows, draw the mechanism of the Pinner synthesis of pyrimidine (3): CH3 CH3 HCI NH2 H3C HN CH3 H;C CH3 1

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter19: Enolate Anions And Enamines

Section: Chapter Questions

Problem 19.68P

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