Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 25.1, Problem 1COMQ
Which of the following would not be consistent with the idea that a disorder has a genetic component?
a. The disorder is more likely to occur among an affected person’s relatives than in the general population.
b. The disorder can spread to individuals sharing similar environments.
c. The disorder tends to develop at a characteristic age.
d. A correlation is observed between the disorder and a mutant gene.
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Which of the following would not be consistent with the ideathat a disorder has a genetic component?a. The disorder is more likely to occur among an affectedperson’s relatives than in the general population.b. The disorder can spread to individuals sharing similarenvironments.c. The disorder tends to develop at a characteristic age.d. A correlation is observed between the disorder and amutant gene.
We often speak of diseases such as phenylketonuria (PKU) andachondroplasia as having a genetic basis. Explain whether the followingstatements are accurate with regard to the genetic basis ofany human disease (not just PKU and achondroplasia).A. An individual must inherit two copies of a mutant allele to havedisease symptoms.B. A genetic predisposition means that an individual has inheritedone or more alleles that make it more likely that she or he willdevelop disease symptoms than other individuals in a populationwill.C. A genetic predisposition to develop a disease may be passedfrom parents to offspring.D. The genetic basis for a disease is always more important thanthe environment.
Monozygotic twins:
Question 2 options:
a)
Share 50% of their genetic material and if one twin has schizophrenia the risk of the other having the illness if 40-50%
b)
Share 100% of their genetic material and if one twin has schizophrenia, the risk of the other having schizophrenia is 10-15%
c)
Share 100% of their genetic material and if one twin has schizophrenia, the risk of the other having schizophrenia is 40-50%
d)
Share 50% of their genetic material and if one twin has schizophrenia the risk of the other having the illness is 10-15%
Chapter 25 Solutions
Genetics: Analysis and Principles
Ch. 25.1 - Which of the following wouldnotbe consistent with...Ch. 25.1 - 2. Assuming complete penetrance, which type of...Ch. 25.1 - 3. Which of the following is not a common...Ch. 25.1 - Prob. 4COMQCh. 25.2 - Prob. 1COMQCh. 25.2 - Haplotype association studies are aimed at the...Ch. 25.3 - 1. Which of the following is not a method used in...Ch. 25.3 - 2. Which of the following prenatal genetic testing...Ch. 25.4 - Prob. 1COMQCh. 25.5 - 1. An oncogene is produced from a ________that has...
Ch. 25.5 - Which of the following is a type of genetic change...Ch. 25.5 - 3. Tumor-suppressor genes promote cancer...Ch. 25.5 - 4. Normal (nonmutant) tumor-suppressor genes often...Ch. 25.5 - Prob. 5COMQCh. 25.6 - Prob. 1COMQCh. 25 - 1. With regard to pedigree analysis, make a list...Ch. 25 - 2. Explain, at the molecular level, why human...Ch. 25 - 3. Many genetic disorders exhibit locus...Ch. 25 - Prob. 4CONQCh. 25 - Prob. 5CONQCh. 25 - Figure 25.1 illustrates albinism in two different...Ch. 25 - Prob. 7CONQCh. 25 - Prob. 8CONQCh. 25 - Ehler-Danlos syndrome is a rare disorder caused by...Ch. 25 - 10. Hurler syndrome is due to a mutation in a gene...Ch. 25 - Like Hurler syndrome, Fabry disease involves an...Ch. 25 - Achondroplasia is a rare form of dwarfism caused...Ch. 25 - Prob. 13CONQCh. 25 - 14. Marfan syndrome is due to a mutation in a...Ch. 25 - 15. Sandhoff disease is due to a mutation in a...Ch. 25 - Describe the two assumptions that underlie the...Ch. 25 - Prob. 17CONQCh. 25 - What is a prion? Explain how a prion relies on...Ch. 25 - 19. Some people have a genetic predisposition for...Ch. 25 - What is the difference between an oncogene and a...Ch. 25 - Prob. 21CONQCh. 25 - Prob. 22CONQCh. 25 - Prob. 23CONQCh. 25 - Prob. 24CONQCh. 25 - Prob. 25CONQCh. 25 - Prob. 26CONQCh. 25 - Prob. 27CONQCh. 25 - With regard to cancer cells, which of the...Ch. 25 - Prob. 29CONQCh. 25 - 1. Which of the following experimental...Ch. 25 - Prob. 2EQCh. 25 - 3. What is meant by the term genetic testing? How...Ch. 25 - Prob. 4EQCh. 25 - 5. Chapter 21 describes a method known as Western...Ch. 25 - 6. An experimental assay for the blood-clotting...Ch. 25 - 7. Discuss ways to distinguish whether a...Ch. 25 - 8. The codon change (Gly-12 to Val-12) in...Ch. 25 - Explain how DNA microarrays are used in molecular...Ch. 25 - Make a list of the benefits that may arise from...Ch. 25 - 2. Our government has finite funds to devote to...Ch. 25 - Prob. 3QSDC
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- Are the following examples a description of genetics at the molecular, cellular, organismal, or populational level? A. People with cystic fibrosis have lung problems due to a buildup of mucus in their lungs B. The mutant CF gene encodes a chloride transporter that doesn't transport chloride ions very well. C. A defect in the chloride transporter causes a salt imbalance in lung cells.arrow_forwardFigure 3 shows the karyotypes of two individuals suffering from a genetic disorder. a) Name the genetic disorder for individuals A and B. b) Give three characteristics of individual B. c) What is the gender of individual A?arrow_forwardConsider an autosomal recessive disease in which an individual must inherit two recessive alleles to display the disease phenotype. What is the probability that a woman who is a heterozygous for the trait and a man who is homozygous for the dominant allele will produce an offspring with the autosomal recessive phenotype? Assume no new mutations occur. Select one 1.) 100% 2.)25% 3.) 0% 4.)50% 5.) More information is neededarrow_forward
- When a disease is due to polygenic inheritance, the following is probably true: A. Many factors, both genetic and environmental, contribute to the disease traits. B. It is caused by one gene with a large number of alleles. C. It affects a large number of people. D. It has many different symptomsarrow_forwarda. Each person inherits one copy of the Huntington's Disease gene from each parent. Explain why the negative control sample (from an unaffected individual) only produced one band. b. Explain why the positive control sample (from an individual affected by Huntington’s disease) produced twobands.arrow_forwardWhich of the following is true regarding understanding the results of genetic testing? A. If the test shows that you have the allele for a genetic disorder, you may be able to reduce your risk of developing that disorder with lifestyle changes. B. If the test shows that you have the allele for a genetic disorder, you will, eventually, show symptoms of that disorder. C. Because we know the functions of all the genes in the human genome, genetic tests can give you complete and accurate information regarding your medical health. D. If the test shows that you do not carry the allele for a particular disorder, there is no chance that you will get that disorder.arrow_forward
- Select all the characteristics that make sickle-cell disease a good candidate to study genetic diseases. (Check all that apply.) Check All That Apply It is easily identifiable by a physical characteristic.It is easily identifiable by a physical characteristic. It results from a single change in a single gene.It results from a single change in a single gene. It can be influenced by the environment.It can be influenced by the environment. The sickle-cell inheritance pattern is not influenced by other genes.The sickle-cell inheritance pattern is not influenced by other genes.arrow_forwardFor gain-of-function disorders, which of the following treatment strategies is the be . A. Gene augmentation B.Supply healthy cells . C.Supply normal form of proteins encoded by wild-type allele . D. Gene silencingarrow_forwardExplain why you agree or disagree with each of thefollowing statements:a. We should not worry much about exposure totoxic chemicals because almost any chemical, at alarge enough dosage, can cause some harm.b. We should not worry much about exposureto toxic chemicals because, through geneticadaptation, we can develop immunities to suchchemicals.c. We should not worry much about exposureto toxic chemicals because we can use geneticengineering to reduce our susceptibility to theireffects.d. We should not worry about exposure to a chemical such as bisphenol A (BPA) because it has notbeen absolutely proven scientifically that BPA haskilled anyone.arrow_forward
- Explain the following diagram. It refers to a pedigree on the disease called phenylketonuria. Briefly explain about the disease; include biochemical and genetic aspects. Then interpret the pedigree. Say what type of inheritance the condition exhibits.arrow_forwardIn a particular family, children of a diseased mother are all affected, and their maternal grandmother was also affected. But the cousins (children of maternal uncle) are not affected. No disorders were recorded in the paternal side. Can you identify the type of this disorder and provide justifications in support of your identification?arrow_forwardBelow is a pedigree of a human blinding disease. Use this pedigree to answer the following questions. If this is disease has an autosomal recessive inheritance pattern, what is the probability that if individuals IV-5 and III-5 had and offspring it would exhibit the disease? a) 25% b) 33% c) 11% d) 17% e) 6%arrow_forward
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