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- O. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S FHemophilia is determined by genes on the X chromosome in humans. Assume that a phenotypically normal woman whose father had hemophilia is married to a normal man. 1) What is the probability that their first son will have hemophilia? 2) What is the probability that their first daughter will have hemophilia?A form of hemophilia is caused by a sex-linked (X-linked) recessive gene. A phenotypically normal woman whose father had hemophilia marries a man who suffers with hemophilia. What is the probability that their first daughter will have hemophilia?
- Hemophilia A, a condition in which blood does not clot properly, is a recessive trait located on the X chromosome (Xh). A woman heterozygous for the trait marries a normal male. What is the probability that this couple will have hemophiliac daughters? What is the probability that this couple will have hemophiliac sons?Neurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of the skin or in nerve tissues. What is the probability that individuals II-1 and II-2 will have a genetic son with NF1? Find the image attached.Why doesn’t the father (II-1) have the disease breast cancer? What is the formal name for an individual having the gene but not showing the trait?
- A man with thalassemia minor marries a normal woman. What phenotypic ratios of thalassemia-affected children might these parents expect?A haemophilic man marries a normal homozygous woman. What is the probability that their daughter will be haemophilic?Hemophilia A is caused by a recessive X-linked allele that encodes a defective form of a clotting protein. If a affected father and a mother who is known to not be a carrier have children, what percentage of female offspring will have hemophilia?
- Ch. 14-9 Mutations in the genes for clotting factor VIII and IX cause hemophilia A and B, respectively. A woman may be heterozygous for mutations in both genes, with a mutated factor VIII allele on one X chromosome, and a mutated factor IX allele on the other. All of her sons should have either hemophilia A or B. However, on rare occasions, one of these women gives birth to a son who does not have hemophilia, and his one X chromosome does not have either mutated allele. Explain.Ch. 14-3 Marfan syndrome (Section 13.5) ) is inherited in an autosomal dominant pattern. What is the chance that a child will inherit the associated allele if one parent does not carry it and the other is heterozygous?If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this an indication that there is a genetic contribution to these traits? What would you do to confirm that genetics is involved in this condition?