Wild-type Mutant 1 Mutant 2 Mutant 3 Stop silent DNA 3 CTT 5 5 3 5 Val missense 3CTC 5 5 GAG 3 mRNA GAA 3 5 GAA 3' CAT5 GTA 3 5 GUA 3 5 GAG 3 3 ATT 5 5 TAA 3 5' UAA 3¹ frameshift--extensive missense Amino acid a Glu d 9 Glu substitution nonsense b h Type of mutation N/A insertion or deletion frameshift--immediate nonsense C Effect on polypeptide normal
Wild-type Mutant 1 Mutant 2 Mutant 3 Stop silent DNA 3 CTT 5 5 3 5 Val missense 3CTC 5 5 GAG 3 mRNA GAA 3 5 GAA 3' CAT5 GTA 3 5 GUA 3 5 GAG 3 3 ATT 5 5 TAA 3 5' UAA 3¹ frameshift--extensive missense Amino acid a Glu d 9 Glu substitution nonsense b h Type of mutation N/A insertion or deletion frameshift--immediate nonsense C Effect on polypeptide normal
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter30: Protein Synthesis
Section: Chapter Questions
Problem 4P: Codon-Anticodon Recognition: Base-Pairing Possibilities (Integrates with Chapter 11.) Draw base-pair...
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