Which of the following statements is true? Not all inheritance patterns follow a strict dominant/recessive relationship O Different inheritance patterns are explained by a variety of different molecular mechanisms O Geneticists want to understand both inheritance patterns and the underlying molecular mechanisms that make them happen O All of the above
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- Hi, I'm having trouble with my study guide for my upcoming genetics exam. If someone could please help with work shown and an explanation it would help so much! Thank you!! 2a. The pedigree below represents inheritance of rare condition. What pattern of inheritance is most consistent with the data? Assign alleles to all individuals to support your answer. If an allele is unknown, assign it a ? symbol. NOTE: Individuals whose phenotype or genotype cannot be determined are assumed to be unaffected and homozygous, unless otherwise indicated. 2b. In addition to the alleles you’ve indicated, describe 2 overall features of the pedigree that make it consistent with your chosen form of inheritance. 2c. Based on your mode of inheritance, what is the probability that the child of couple IV-4 x IV-5 will be affected? Show your work. attached is the pedigreeDATA | The following pedigree illustrates the inheritance of ringed hair, a condition in which 28. ANALYSIS each hair is differentiated into light and dark zones. What mode or modes of inheritance are possible for the ringed-hair trait in this family? 2 II 2 II 3 4 5 IV I P 2 Pierce, Genetics: A Conceptual Approach, 7e © 2020 W. H. Freeman and Company 2.I'm having trouble with my genetics study guide, and am stuck on this question. If someone could explain it with the work it would help me so much. Thank you! In humans, the inheritance of the ABO blood group system exhibits both complete dominance (alleles IA and IB are dominant to allele i) and codominance (alleles IA and IB). In addition, thalassemia shows incomplete dominance; heterozygotes (Tt) exhibit a mild form of the disease (thalassemia minor) and homozygotes (tt) have a more severe form (thalassemia major). A man has blood type A and his mother has blood type O. His wife has blood type AB. Both members of the couple have thalassemia minor. What is the probability that they will have a child with: a. thalassemia minor and blood type A? b. no anemia and blood type AB? c. thalassemia major and blood type B?
- Let us practice it again! Analyze the pedigree below to answer the questions that follow. Huntington's disease a disorder in which nerve cells waste away, or disintegrate, is passed down through families. certain parts of the brain Huntington's diseate llustration ereated in htps://pregenygenetion.com/ 1. What members of the family above are affected with the Huntington's disease? 2. Tnere are no carriers ior Huntungton's disease you either have it or you do not. Is Huntington's disease caused-by a dominant or recessive trait? 3. Identify the genotypes of the following individuals using the pedigree above. (homozygous dominant, homozygous recessive, heterozygous). I- 1 II -1: II -3: III - 4 : 4. How many children did individuals I-1 and I-2 have? 5. How many girls did II-1 and II-2 have? How many have Huntington's Disease? 6. How are individuals III-2 and II-4 related? I-2 and III-5?Could the characteristic followed in the pedigree be caused by an autosomal dominant disease? Why or why not? 3 4. O No, the offspring of 1-3 and I-4 contradict an autosomal dominant inheritance O No. the offspring of 1-1 and I-2 contradict an autosomal dominant inheritance O Yes, all individuals fit the autosomal dominant inheritance pattern ONo, the offspring of II-3 and -4 contradict an autosomal dominant inheritanceQuestion 3 Review Mendelian genetics. Match the term and its description. Each term can only be used once. The two alleles for a heritable character separate (segregate) during gamete formation and end up in different gametes | Choose ) Each pair of alleles segregates independently of any other pair of alleles during gamete formation [ Choose ] An organism with two identical alleles for a character [ Choose ] an organism's physical appearance | Choose ) the breeding the mystery individual with a homozygous recessive individual [ Choose ) > > > > >
- QUESTION 5. The pedigree below follows the appearance of a rare autosomal dominant condition resulting in malformation of limbs through a family. What is the penetrance of this trait? i.e., What is the ratio between the number of individuals in the pedigree who display the trait (numerator) and the number of individuals you know from the pedigree must have the trait-determining genotype (denominator)? Enter your answer in the form of a fraction without any spaces. e.g., If your answer is “one-fourth”, enter: 1/4I am having trouble solving this problem sets about sex-linked inheritance. Hemophilia is a recessive X linked genetic disorder (refer to BIOL 40 B), a medical condition in which the ability of the blood to clot is severely reduced, causing the sufferer to bleed severely from even a slight injury. The condition is typically caused by a hereditary lack of a coagulation factor, most often factor VIII or factor IX (refer to Bio 40 B Textbook chapter 19 on Blood). Based on a recent study that used data collected on patients receiving care in federally funded hemophilia treatment centers during the period 2012-2018, as many as 33,000 males in the United States are living with the disorder. Males inherit the X chromosome from their mothers and the Y chromosome from their fathers. Females inherit one X chromosome from each parent. Thus, males can have a disease like hemophilia if they inherit an affected X chromosome that has a mutation in either the factor VIII or factor IX gene. Females can…Null mutations are valuable genetic resources becausethey allow a researcher to determine what happens to anorganism in the complete absence of a particular protein. However, it is often not a trivial matter to determinewhether a mutation represents the null state of the gene.a. Geneticists sometimes use the following test forthe nullness of an allele in a diploid organism: If theabnormal phenotype seen in a homozygote for theallele is identical to that seen in a heterozygote(where one chromosome carries the allele in question and the homologous chromosome is known tobe completely deleted for the gene) then the alleleis null. What is the underlying rationale for thistest? What limitations might there be in interpreting such a result?b. Can you think of other methods to determinewhether an allele represents the null state of a particular gene?
- FAlpQLSfiOhfAvlhxzCSiUll_6rt-nU5b0WI73UmWOxkOw8OCwk01ng/formResponse B 1 2 Bb x Bb b 4 The fur in both parents in this cross is * 1 B B Bb x Bb b 3 4 brown black O homozygous dominant homozygous recessive 3. 近Question 10 What can you tell about the condition that is depicted in the pedigree shown above? 4 II 1 3 4 5 6 7 8 9 10 11 IV 6 7 8 The trait is autosomal recessive. O The trait is autosomal dominant. O The trait is sex-linked dominant. O It is impossible to tell.Question 6 Review non Mendelian genetics. Match the term and its description. Each term can only be used once. the phenotype of F1 hybrids is somewhere between the phenotypes of the two parental varieties | Choose | two dominant alleles affect the phenotype in separate and distinguishable ways | Choose | Most genes exist in populations in more than two allelic forms | Choose | Most genes have multiple phenotypic effects [ Choose J multiple genes independently affect a single trait | Choose | expression of a gene at one locus alters the phenotypic expression of a gene at a second locus [ Choose J > > > >