Which enzyme activity would be inhibited if fluorodeoxyuridine-5 monophosphate is present? thymidylate synthase Oribonucleotide reductase Odihydrofolate reductase Othymidine kinase
Q: The degradation of CH3 (CH₂ )10 - COOH via the beta-oxidation pathway requires: 6FAD + 6NAD+ +…
A: Fatty acids metabolism involves β-oxidation which happens in the mitochondrial matrix. In…
Q: 3. Pyrozole has been proposed as a possible nontoxic inhibitor of LADH-catalyzed ethanol oxidation.…
A: Since you have posted a question with multiple sub parts, we will provide the solution only to the…
Q: The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pKa of 3.86.…
A: Dissociation of a weak acid is mathematically described by the Henderson-Hasselbalch equation: pH =…
Q: The naturally occurring opioid met-enkephalin is a peptide with the structure Tyr- Gly-Gly-Phe-Met.…
A: Amino acids are zwitterions having both positive and negative charges at neutral pH. The net charge…
Q: The textbook author admits the number of protons pumped from the matrix to inter-membrane space by…
A: Oxidative Phosphorylation: In a sequence of redox reactions, electrons are transferred from one…
Q: Write a scheme for the formation of ribose-3-monophosphate. Biological role of the formed compound.
A: Ribose 5-phosphate is the intermediate byproduct of pentose phosphate pathway (PPP). It is comprised…
Q: 2. Calculate the energy released by the burning, or oxidation, of 1 g of glucose, C6H12O6 (Figure…
A: Carbohydrates or carbs are maconutrient consisting of Carbon, hydrogen and oxygen atoms. In nature…
Q: When an enzyme interacts with the substrate, which of the following occurs?
A: Enzymes are high molecular-weight proteins that catalyse biochemical reactions. They are also called…
Q: A competitive inhibitor diminishes the rate of catalysis: A) By reducing the proportion of enzyme…
A: The enzymes are biological catalysts that increases the rate of biological reactions. The enzymatic…
Q: What are some applications for metalloproteins?
A: Metalloproteins are the types of proteins or enzymes that binds to a metal ion as a cofactor in…
Q: Fluoroacetate is used as a poison for rat control. After entering a cell, fluoroacetate is converted…
A: The first step in the citric acid cycle is the formation of citric acid, by the condensation of…
Q: Isozymes: d) One way of regulating metabolic pathways is through isozymes. What is an isozyme? e)…
A: Introduction: Every living system requires various forms of specific enzymes in order to increase…
Q: Following several days at high altitude the body responds to the decreased oxygen content of the…
A: Hemoglobin is the heme or iron-containing oxygen-transport metalloprotein that carries oxygen in…
Q: There are eight chemical reactions that occur in the citric acid cycle process. The reactions of…
A: The Krebs cycle or citric acid cycle occurs in the mitochondria and provides electrons for oxidative…
Q: . What is the nucleotide sequence of the complementary strand of the DNA molecule:…
A: DNA is the genetic material in most organisms. During transcription RNA Polymerase synthesizes the…
Q: Explain why both ATP and NADPH are required for the operation of the Calvin-Benson-Bassham cycle,…
A: Calvin-Benson-Bassham cycle is commonly known as Calvin cycle or Dark reactions of photosynthesis,…
Q: Enzymes are important molecules in biochemistry that catalyze reactions. The energy diagram…
A: Since there are multiple questions and which question is to be solved has not been specified, as per…
Q: Base Adenine Guanine Cytosine Thymine Type of Bases Ring structure Number of hydrogen bonds…
A: Nucleic acid can be of 2 types: DNA (deoxyribonucleic acid) RNA (ribonucleic acid) DNA has a…
Q: Uncouplers of oxidative phosphorylation are all expect: Select one: O a. thermogenin O b.…
A: INTRODUCTION: (Oxidative phosphorylation) The process by which ATP is formed as a result of the…
Q: Acetyl COA (ACC) is a critically important molecule in metabolic pathways. This molecule can be used…
A: ACC is the rate limiting enzyme of fatty acid synthesis pathway. ACC catalyzes the conversion of…
Q: -11- E + SF k_1 ES ₂ E + P k2 › 10.0 + S ↓↑K IS ESS st Based on this model, please answer the…
A: The cessation of enzymatic activity is generally known as enzyme inhibition. It is generally of two…
Q: Why is derivatization (i.e., transesterification) of triglycerides or lipids to fatty acid methyl…
A: Triglycerides are fatty acid esters of glycerol, where three fatty acid molecules are linked to one…
Q: What test tube will show positive starch hydrolysis and negative starch hydrolysis?
A: Starch is the most common carbohydrates (polysaccharides) which is a polymer of several glucose…
Q: The patient has mechanical jaundice. Will it affect the absorption of fat-soluble vitamins? There…
A: To live a healthy and active life, humans need a variety of nutrients. Good nutrition, or the…
Q: The carbon skeletons of many amino acids can be used to replenish the intermediates of the citric…
A: Since you have posted multiple MCQ questions, we will provide the solution only to the first three…
Q: could the answer be no cooperativity as well?
A: Cooperative binding is a phenomenon where the binding of one molecule increases the affinity of the…
Q: Problem. The student conducted a chemical experiment to prove the reducing properties of maltose…
A: Chemically carbohydrates are polyhydroxy aldehydes or ketones. They have the general formula :…
Q: 1. Carbohydrate digestion: gastrointestinal enzymes and the optimal pH environment for their…
A: Carbohydrates are key energy source in our body and basic subunit of carbohydrate is…
Q: Question 14 The first three amino acids in a protein are lysine, glutamine, and serine. T describes…
A: The four classes of biological macromolecules are proteins, nucleic acids, carbohydrates and lipids.…
Q: a) Describe the three irreversible reactions of the Citric Acid Cycle. Ensure to indicate their…
A: Krebs cycle or tricarboxylic acid (TCA) cycle in aerobic organisms is the final stage of catabolism…
Q: Signaling by tyrosine kinase receptors is generally associated with all of the following except: OA)…
A: A hormone is a class of signaling molecules in multicellular organisms that are sent to distant…
Q: Give an overview of Tumor necrosis factor (TNF) signaling, and discuss the nature of the TNF ligand…
A: TNF signaling is an apoptotic signaling pathway that causes programmed cell death due to external…
Q: Starch is an example of a O none of the other answers are correct O fat O carbohydrate O protein…
A: The four classes of biological macromolecules are proteins, nucleic acids, lipids and carbohydrates.…
Q: Which of the following regarding the Electron Transport Chain is INCORRECT? It can accept electrons…
A: Aerobic metabolism of 1 molecule of glucose can produce 10 NADH (6 from acetyl CoA in TCA cycle + 2…
Q: Which of the following is a ketone body? O Pyruvate Acetoacetic acid O Lactic acid O Glycogen
A: Ketone bodies contain ketone groups and are produced in the liver from fatty acids. The process of…
Q: Which of the choices are types of posttranslational modifications a newly synth choices that apply.…
A: Posttranslational modifications are the amino acid side chain modification in some proteins…
Q: What is the complete base composition (in %) of a double-stranded eukaryotic DNA that contains 16%…
A: Introduction DNA acts as a genetic material in our body. It is a self replicating molecule. DNA…
Q: How many molecules of NADH and FADH2 are made if one glucose molecule goes through glycolysis and…
A: Cellular respiration is a collection of three metabolic pathways that generate ATP the energy…
Q: Classify each metabolic reaction as an oxidation-reduction reaction, isomerization reaction, or…
A: Metabolism is the total of all chemical transformation that takes place in a living cell. One…
Q: Lactate dehydrogenase (LDH): structure, characteristics, isoforms and their diagnostic significance.
A: Enzymes are bio-catalyst that participate in biochemical process and they are highly specific in…
Q: 2. What is the terms used to describe what is happening to the members of the electron transport…
A: The electron transport system (ETC) is the series of redox reaction in which involved a series of…
Q: A total of 7.21 g of dry mixture with a protein content of 89.2% (w/w) determined by Kjeldahl…
A: % w/w tells us the grams of analyte in 100g of mixture. Hence, a protein content of 89.2% (w/w)…
Q: The PDH complex is a logical point of regulation in metabolism, as it links two major catabolic…
A: Cellular respiration is a collection of three metabolic pathways that generate ATP the energy…
Q: What is a kilocalorie (kcal)? O Unlike 1 food calorie, this is the amount of energy needed to raise…
A: Introduction The calorie is a unit of energy. The amount of energy in any food item is measured in…
Q: Graph a double reciprocal plot that satisfy the following: a. Michaelis-Menten kinetics enzyme,…
A: For a one-substrate enzyme-catalyzed reaction, the Michaelis-Menton equation shows the quantitative…
Q: For class I MHC, which of the following statements are correct? P. They are expressed on all…
A: MHC are proteins encoded by a huge complex of genes called the major histocompatibility complex…
Q: Sucrase has an optimum temperature of 37°C and an optimum pH of 6.2. Determine the effect of the…
A: Since you have posted multiple questions with multiple sub parts, we will provide the solution only…
Q: 1. Draw the open-chain form for each of the following monosaccharides. CH OH HOOH НО CH₂OH OH OH он…
A: Monosaccharides Carbohydrates are polyhydroxy aldehydes or ketones. They can be classified as…
Q: Give the following information about the "Protein Banding Pattern" - Methodologies - Advantages -…
A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…
Q: DETAILS 09 Select all of the following half reactions that require energy (work) to proceed as…
A: The reactions that require energy to proceed are called endergonic reactions. The half reactions are…
Step by step
Solved in 2 steps
- In class, I mentioned that fructose is metabolized differently in the liver compared to glucose. Refer to the figure shown below to calculate the number ofATPs you would expect from the metabolism of fructose in the liver. Show your work! Fructokinase Fructose Fructose-1-P АТР ADP Aldolase B Dihydroxy- acetone phosphate Glyceraldehyde АТР Triose kinase Triose phosphate isomerase ADP 4 - Glyceraldehyde-3-P Glycolysis Руruvate Acetyl-CoA Fatty acids and triglyceridesIn serine protease catalytic triad mechanism, the first and second products that leaves the active site are Carboxylic acid and amide respectively Amide and carboxylic acid respectively Ester and amide respectively Carboxylic acid and ester respectivelyIn this step of purine biosynthesis, which functional group gets activated by ATP Pribose NH, ATP Carboxyaminolmidazole ribonedeotide Asp AD Fumarate Pribose NH, S-Aminolmidazole- 4(N-succinylcarboxamide) ribonucleotide O Carboxyaminoimidazole ribonucleotide COOH O Carboxyaminoimidazole ribonucleotide NH2 O Asp side chain COOH O Asp main chain NH2 O Asp main chain COOH
- Consider the mechanism of enolase, as indicated below. Which of the following correctly describes the roles of the Mg2+ as illustrated in the figure? (This is a multi- select question). Mg2+ Mg2 Enolase PO3- OH -C-C-H H OH HO H-N-H Lys 345 Glu211 2-Phosphoglycerate bound to enzyme Mg2+ Mg2 PO3- OH C-C-H OH HO H H-N*-H Lys 345 O Glu211 Enolic intermediate HOH PO3- H Phosphoenolpyruvate The metal ion (Mg2+) is helping to stabilize the extra negative charge that developed on the carboxyl group in the enolic intermediate. The metal ion (Mg2+) is serving as a general base, removing a proton in order to improve the quality of the nucleophile. The metal ion (Mg2+) is assisting in the oxidation of the carboxyl carbon through metal ion catalysis. The metal ion (Mg2+) is helping to orient the substrate properly in the active site. The metal ion (Mg2+) is accepting a proton in order to improve the quality of the leaving group.Based on the image below, select the correct statement HN Aspartate Rib-P Inosinate (IMP) IMP H₂O OOC-CH₂- COO NH Fumarate N 274 adenylosuccinate lyase Rib-P Adenylosuccinate GTP GDP + P₁ adenylosuccinate IMP synthetase NAD+ NADH + H+ dehydrogenase Figure 22-36 Lehninger Principles of Biochemistry, Sixth Edition ©2013 W. H. Freeman and Company H HN H -N Gin Rib P Xanthylate (XMP) NH₂ Rib P Adenylate (AMP) Glu ATP AMP + PP₁ XMP-glutamine amidotransferase HN H₂N O GTP is phosphorylated in the conversion of IMP to GMP GTP is phosphorylated in the convertion of IMP to AMP GTP is dephosphorylated in the conversion of IMP to GMP O GTP is dephosphorylated in the conversion of IMP to AMP Rib-P Guanylate (GMP) GMPa What would be the appropriate name for an enzyme that catalyzes each of the following reactions: b H3C iOH OH NH₂ alanine ligase alanine oxidoreductase alanine isomerase alanine transferase OH H3C CH3 H3C NO₂ propanone transferase propan-2-ol hydrolase propan-2-ol oxidoreductase propan-2-ol isomerase OH H3C CH3
- NH₂ CH3 Methyltransferases NH₂ OH OH S-Adenosylmethionine (SAM) Transamination Phosphate transfer Protein Acetyl transfer Transmethylation CH3 DNÁ CH3 NH₂ What metabolic reaction is best represented by this chemical equation? SAH-Hydrolase (SAHase) NH₂ OH OH S-Adenosyl-L-Homocysteine (SAH) I но. #M OH OH Adenosine NH₂ NH₂ SH HomocysteineDecide whether each of the following statements is true about leucine transaminase. It's an enzyme, and leucine is its substrate. It speeds up the rate at which leucine is converted to other substances. It's a small molecule, with a molecular weight around 50 mol If you were to write a chemical equation for certain biochemical reactions of leucine, leucine transaminase would appear on both sides. Otrue Ofalse Otrue Ofalse Otrue Ofalse Otrue Ofalse Xuizzes/67365/take Based on the image below, select the correct statements. Note: There may be more than 1 correct response. I Ribose 5-phosphate ribose phosphate pyrophosphokinase (PRPP synthetase) glutamine-PRPP amidotransferase adenylosuccinate synthetase AMP > 5-Phosphoribosylamine I adenylosuccinate PRPP lyase 9 steps Adenylosuccinate AMP IMP <-- ADP - AMP <-- GMP <-- IMP IMP dehydrogenase <- GMP - XMP ADP ATP GMP يمد XMP-glutamine amidotransferase Increased levels of ADP inhibit the production of PRPP. Increased levels of GMP inhibit the production of XMP. O Increased ADP activates PRPP synthase to increase PRPP levels. Increased IMP activates glutamine-PRPP amidotransferase to further increase IMP levels. 8 OBC
- The enzyme chymotrypsin, catalyses the hydrolysis of nitrophenyl acetate and pther acyl esters. Name the amino acid residue, the side chain of the residue, and the type of bond/linkage involved in the formation of the acyl-emzyme complex during catalysis.Phosphoribosyltransferase (PRT) catalyzes the attachment of a salvaged purine nitrogenous base on the activated form of ribose-5-phosphate called 5-phosphoribosyl- α α-pyrophosphate ( α α-PRPP). True Or FalseShown below is a substrate for a Trypsin. Draw the mechanism for this serine protease using the artificial substrate. Be sure to draw the catalytic triad, and show the role of the oxyanion hole. Draw the complete structure of every intermediate and product and PUSH ARROWS!!!!! Do not abbreviate structures using R and R' H₂N _N_CH. сно CH₂ CH₂ CH₂ NH d=19H₂ NH₂ O CH- H₂C HN O CH