What is a pharmacopeial monograph? Based on the USP XXII and NF XVIII, list the part of a monograph of the following: crude drug, natural product, and natural derivatives.
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- Give one advantage and one disadvantage of pharmaceutical solid dosage forms. Explain each advantage and disadvantage thoroughly.What is DPI? What are the advantages of DPI over MDI? How drug is aerosolized from a DPI system? Please answer at your own words.What is the definition of a crude drug? Describe the drug's origins.
- Name the three basic classes of drug targets in medicinal chemistry and indicate, which are the most/least important as targets for biologics? I don't sure if I answer these questions correctly. Hope someone can give me confirmation and explain to me how enzymes will be affected by bioloigcs? My answer so far: The three common classes of drug targets are; receptors, nucleic acid, and enzymes. As a target for biologics, the least important will be a nucleic acid, and the most important will be receptor and second enzymes. Biologic drugs such as monoclonal antibodies will bind to the antigens, which are overexpressed receptor that need to be deactivated. In this case, the monoclonal antibodies will act as an antagonist and block the ligand from binding to the antigens, which are extensively presented in cancer cells. In addition, it can also affect enzymes by.......?Name three reasons why a drug has different dosage forms.Doris has reconstituted a bottle of Cefprozil® Oral Suspension to fill a patient's prescription. The prescription calls for 400 mg CefprozilⓇq12h for 7 days. Doris needs to know if the amount of reconstituted medication in the bottle will be enough to last the patient for 7 days. Calculate the total amount of medication in the bottle after this medication has been reconstituted: TEVA Seferle, PA 18960 PHARMACEUTICALS USA SHAKE WELL BEFORE USING KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN 5 mL (approx. one teaspoonful) of suspension. Phenylketonurics: This product contains 10.1 mg of phenylalanine per Store constituted suspension in refrigerator. Discard after 14 days Ruv. A 7/2005 L52974 NDC 0093-1075-78 CEFPROZIL for Oral Suspension USP 125 mg/5 mL* Each 5 mL, when constituted according to directions, contains 125 mg anhydrous cetprozil, Ronly 75 mL (when mixed) TEVA To the Pharmacist: Prepare suspension at time of dispensing. Add to the bottle a total of 59 ml water.…
- Question 3 Briefly discuss the principle and significance of the following tests used in the quality control of natural product derived drugs. a) Acid value of lipids b) Loss on drying of crude drugs Question 4Using conversion factors, solve each of the following clinicalproblems:a. A nurse practitioner prepares an injection of promethazine,an antihistamine used to treat allergic rhinitis. If thestock bottle is labeled 25 mg /mL and the order is a doseof 12.5 mg, how many milliliters will the nurse draw up inthe syringe?b. You are to give ampicillin 25 mg/kg to a child with a massof 62 lb. If stock on hand is 250 mg /capsule, how manycapsules should be given?Enumerate and describe at least three (3) big scale pharmaceutical methods on reducing particle size.
- a) Explain the general advantages in the use of radiopharmaceuticals for treatment as opposed to irradiation using external sources of radiation. b) Relate these advantages to explain why radiopharmaceuticals are often used in the treatment of i) prostate cancer(brachytherapy) ii) thyroid cancer (iodine-131 treatment)The reason why most antibiotics as oral suspension dosage forms are commercially available as dry powders, to be reconstituted with water just prior to dispensing, is:TRUE OR FALSE Properties of a drug suitable for transdermal use include: High molecular mass Low lipophilicity Low required daily dose Low potency High partition coefficient Problems with opioid TDDS include: Poor patient compliance Allergy Constipation Respiratory depression Cognitive dysfunction