What enzyme(s) is/are specifically required for the oxidation of a Aeven monounsaturated fatty acid? (select all that apply) O Methylmalonyl CoA Mutase O enoyl-CoA Hydratase O43-enoyl-CoA isomerase O Thiolase O2,4-Dienoyl-CoA Reductase OPropionyl-COA carboxylase
Q: Please explain the role of pantothenic acid-derived CoA as a carrier of acetyl group in carbohydrate…
A: Coenzyme A is required for the metabolism of carbohydrates. Pantothenic acid is the prescursor of…
Q: B-oxidation of a 15:0 fatty acid will result in the production of O 7 acetyl CoA, 7 FADH2, and 7…
A: The beta oxidiation occurs in a number of the small cycle steps. Each cycle gives 1 NADh , 1…
Q: Many components of the glycolytic pathway and the citricacid cycle are direct exit or entry points…
A: Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: Glucagon secretion inhibits intracellular acetyl-CoA carboxylase activity through a number of…
A: The hormone glucagon is capable of regulating the activity of acetyl-CoA carboxylase. It activates…
Q: Leucine and Ilysine are ketogenic amino acids. What does that mean for their metabolism? OA) These…
A: Ketogenic amino acids are the amino acid that can be directly degraded into ketone bodies and…
Q: True or false Ketone body synthesis requires transportation of acetyl-CoA through the inner…
A: Acetone, acetoacetate and 3 beta hydroxybutyrate are known as ketone bodies. They are produced from…
Q: During fatty acid biosynthesis, propionyl CoA is the donor of the acetyl group. O True O False
A: Fatty acid biosynthesis occurs in the cytoplasm and endoplasmic reticulum of the cell. They are…
Q: why is much of acetyl-CoA resulting from ethanol metabolism is used in fatty acid synthesis rather…
A: CH3-CH2-OH --------> CH3-COO- Acetyl co A is produced from ethanol by alcohol dehydrogenase by…
Q: CHOOSE THE CORRECT LETTER 1.Which of the following enzymes catalyze the reaction involved in the…
A: The TCA cycle or Kreb's cycle occurs only in the presence of oxygen inside the mitochondrial matrix.…
Q: the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino…
A: Metabolic pathways can be linear , cyclic or spiral. Flow of metabolites through metabolic pathway…
Q: Consider docosanoic acid, C2,H43CO,H. a. Label the a and ß carbons. b. Draw the acyl COA derived…
A: Introduction: Docosanoic acid is a 22 carbon fatty acid.
Q: Which of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O enoyl-ACP…
A: Fatty acid synthase is a multi-enzyme protein that catalyzes Fatty acid synthesis. Its main function…
Q: Which of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O…
A: Fatty acids are long chain carboxylic acids. These are synthesized in cytosol. The precursor is…
Q: In the metabolism of lipids, B-oxidation will yield (n/2) acetyl-CoA fragments from a C fatty acid.…
A: Thank you for the question Answer = The correct answer is option A ( propionyl CoA). Beta…
Q: Acetyt CoA Oxaloscetate CoA NADH Citrate NAD Isocitrate Malste Pumarate NAD NADH FADH, FAD a-…
A: TCA cycle is the tricarboxylic acid cycle which is the second step in cellular respiration that…
Q: 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase) is a very long name for the enzyme…
A: DISCLAIMER: Since you have asked multiple questions, we have solved the first question for you. If…
Q: Which of these statements concerning the following citric acid cycle reaction is true? Malate + NAD*…
A: Introduction: TCA cycle is a cyclic process. As many elements enters and leave the cycle, it should…
Q: The carbon chain of fatty acids is shortened by 2 carbon atoms at a time. This involves successive…
A: A metabolic process that breaks down the fatty acids into a shorter chain along with the release of…
Q: what is the correct sequence of reactions on the given choices with regard to beta oxidation of…
A: Lipid is a biomolecule that is not soluble in water. It plays a vital role as an effective cell…
Q: Hexanoic acid is a 6-carbon saturated fatty acid found in goat's milk. Hexanoic acid also…
A: Fatty acids undergo degradation or beta-oxidation in the matrix of mitochondria inside the cell.…
Q: The peroxisomal enzyme b-ketoacyl–CoA-thiolase does notbind medium-chain acyl-CoA, in contrast to…
A: The peroxisomal enzyme beta-ketoacyl CoA thiolase does not bind medium chain acyl CoA in contrast to…
Q: Match the following metabolites with the correct metabolic pathway v Propionyl-CoA A. Kreb's cycle…
A: Answer: METABOLIC PATHWAYS: These are the seres or linked chemical pathways of metabolites which…
Q: Acetyl-CoA and succinyl-CoA are both highenergy thioesters, but their chemical energy is put to…
A: The tricarboxylic acid (TCA) cycle, is also known as the Krebs or citric acid cycle, is the main…
Q: /hen the acetyl-CoA produced during B-oxidation in the liver exceeds the capacity of the citric acid…
A: The oxidation of some amino acids into fatty acids, as well as glycolysis, is the source of acetyl…
Q: End of Beta Oxidation CO2 ATP H3C COA "ooc, CoA Propionyl - CoA - Carboxylase ADP + PI CH3 (S) -…
A: The dietary lipids are stored in the form of triglycerides. A triglyceride molecule consists of a…
Q: Glucagon secretion causes inhibition of intracellular acetyl-CoA carboxylase activity by several…
A: Glucagon, a hormone, has the ability to regulate the activity of acetyl-CoA carboxylase. It is able…
Q: Citrate Synthase exists as a dimer but can catalyze the formation of only 1 citrate from Acetyl-CoA…
A: The formation of citrate from Acetyl- CoA, and Oxaloacetate is catalyzed by the enzyme citrate…
Q: Pyruvate dehydrogenase catalyzes the conversion of pyruvate to acetyl CoA. In this reaction, one…
A: Pyruvate dehydrogenase Enzyme is a complex of three enzymes that are important for decarboxylation…
Q: Which of the following lipid metabolism enzymes would be functioning in liver during a fast? Choose…
A: When the quantities of circulating glucose and insulin become low during fasting state, which…
Q: Which of the following is an inhibitor of gluconeogenesis? Group of answer choices: -ATP -ADP…
A: Gluconeogenesis is the process of Synthesis of glucose from lactose, pyruvate, glucogenic aminoacids…
Q: Lysine is degraded to acetoacetyl-CoA then to acetyl-CoA, and is described as a _______ amino…
A: Lysine and arginine are broken down into acetoacetyl CoA and Acetyl CoA respectively. The process…
Q: Can you please pick the right answer in each parentheses (a) to (e)?
A: Answer. Pyruvate dehydrogenase complex is an assembly of three individual enzymes. It is the…
Q: What major metabolic substrate do ketone bodies convert into so that they enter the metabolic…
A: Ketone bodies are formed from β-oxidation of fatty acid.
Q: Indicate what will happen ( increase, decrease or no effect) tothe activity of the enzyme or rate of…
A: Metabolism refers to the anabolism as well as catabolism of biomolecules including lipids, proteins,…
Q: . Label alpha (a) and beta ( B) carbons . Draw the acyl CoA derived from this fatty acid . How many…
A: Fatty acid metabolism includes Fatty acid biosynthesis(an anabolic process) and β- oxidation of…
Q: Degradation of fats as an energy source involves all of the following excepta) β -oxidation.b)…
A: Fatty acid metabolism involves various metabolic processes related to fatty acids. Fatty acids are…
Q: Tomorrow morning, you decide to sprint a quick mile before breakfast. Which enzymes will be actively…
A: Metabolic enzymes are involved in anabolism and catabolism of biomolecule to meet the demand of…
Q: CHOOSE THE CORRECT LETTER 1. Condensation of acetyl CoA with oxaloacetate is catalyzed by A. citrate…
A: The citric acid cycle involves the oxidation of acetyl CoA to CO2 and H2O. The cycle starts with the…
Q: Mammals cannot undergo net synthesis of carbohydrate from acetyl-CoA, but the carbons of acetyl-CoA…
A: Glucose is catabolized to generate ATP by respiration. The carbon chain in glucose is oxidized and…
Q: Although glucose cannot be formed from acetyl-CoA, triglycerides can enter the glycolytic pathway…
A: Introduction Fats (or triglycerides) are ingested as food or synthesised by adipocytes or…
Q: rounds of beta axidation are required to produce complete oxidation of this fatty acid: CH3(CH2)7CH…
A: Beta oxidation is a fatty acid (FA) oxidation process which occurs in the mitochondria. Fatty acids…
Q: If Acetyl-CoA carboxylase is used to catalyze the synthesis of malonyl-coA from acetyl-CoA and…
A: Palmitate is a saturated fatty acid made up of 16 carbons. It is synthesized from acetyl CoA by the…
Q: In gluconeogenesis, only the carbon skeletons of amino acids, not fatty acids, are utilised. So how…
A: The metabolic process or cycle in which lipids are digested or broken down to release or create…
Q: Oxaloacetate carries acetyl CoA to the cytosol which is the site of fatty acid biosynthesis. O True…
A: Fatty acids are long chain carboxylic acid molecules. These are synthesized from acetyl CoA in the…
Q: Which of the following statements explains why acetyl-CoA is considered the central molecule of…
A: Introduction: Acetyl-CoA is a membrane-impermeant molecule that contains acetyl-CoA linked to…
Q: In Yeast, pyruvate can be directly converted into: A. acetyl-CoA and ethanol B. acetyl-CoA only C.…
A: Pyruvate is made from the glycolysis of glucose, glycolysis breaks glucose into two pyruvate.…
Q: Release of Acetyl CoA from the ketoacy| CoA is catalyzed by a. Hydratase b.Lipoprotein lipase c.…
A: Biological macromolecules are those large molecules that are necessary for the survival and growth…
Step by step
Solved in 3 steps
- Step 2 of B-oxidation involves a reaction with chemistry characterized as a dehydration. B-Oxidation is shown below. H HO || || C-C-S – CoA FAD но R-CH2- C Acyl-CoA dehydrogenase H-C-C -S- CoA Acetyl-CoA Fatty acyl-CoA H FADH2 - CH2 - -c-S- CoA R- Thiolase Fatty acyl-CoA shortened by two carbons COA-SH H. он Successive cycles R-CH2-C-C- -C-S- CoA R– CH2 C=C-C-S-CoA H B-Ketoacyl-Co.A trans-A²Enoyl-CoA NADH + H* H,0 H H L-Hydroxyacyl-CoA dehydrogenase Enoyl-CoA hydratase R- CH,-c-c-C- S-CoA Но H NAD+ L-B-Hydroxyacyl-CoA True O FalseIdentify a pathway for utilization of the four carbons of acetoacetate in cholesterol biosynthesis. Carry your pathway as far as the rate-determining reaction in cholesterol biosynthesis. Drag the appropriate labels to their respective targets. succinyl-CoA succinate acetyl-CoA CoA-SH acetoacetyl-CoA HMG-CoA 2NADP 2NADPH+ 2H acetoacetate K UHL return to a mevalonate + CoA-SHWhich of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O enoyl-ACP reductase O acetyl CoA carboxylase O 3-hydroxybutyrylACP-dehydratese O B-ketoacyl-ACP reductase
- What is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all that apply. Group of answer choices Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP ReductaseWhat is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all that apply. Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP ReductaseArrange the steps of breakdown of oleic acid (pictured below) in the correct order. 1 2 3 4 5 activation by acyl-CoAsynthe ✓ [Choose ] one cycle ofß-oxidationbeginning at the enoyl-CoAhydratasestep three cycles ofẞ-oxidation five cycles ofß-oxidation activation by acyl-CoAsynthetase enoyl-CoAisomeraseactivity enoyl-CoAisomeraseactivity V one cycle ofß-oxidationbegini V five cycles ofß-oxidation OH
- All of the following are accurate contrasts for beta oxidation vs fatty acid synthesis except which of the following statements? Group of answer choices The hydroxylacyl group differs in stereochemistry between beta oxidation and biosynthesis CoA is the acyl carrier group in beta oxidation, acyl carrier protein is the carrier in biosynthesis The carbon unit resulting from beta oxidation is acetyl-CoA, the carbon unit for biosynthesis is malonyl-CoA FAD is an electron acceptor in beta oxidation, NADP+ is the electron acceptor in biosynthesisC-CH2 + H* CO, + CH,-C-S-COA S-COA Malonyl-CoA Acetyl-CoA Hydrolase Transferase Lyase LigaseWhat is the final reaction in the final round of fatty acid synthase? Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductase
- Using the list of enzymes given below, provide all chemical structures and reactions for complete metabolism of the fatty acids 8:0, 18:145 and 12:247,10. It is unnecessary to repeat a reaction once it has been drawn out previously. Refer to the repeated reaction by group and number. Use the next pages if necessary and clearly identify which fatty acid is being metabolized.What is(are) the product(s) of the thiolase reaction involving a sixteen carbon ß-ketoacyl substrate and CoASH? O A 14 carbon acyl-CoA molecule and acetyl-CoA O An 18 carbon acyl-CoA molecule and acetyl-CoA O acetoacetyl coA O An 18 carbon acyl-CoA moleculeIdentify the components of animal fatty acid synthase (FAS). ☐acyl-CoA dehydrogenase B-ketoacyl synthase ☐acyl-CoA synthetase B-hydroxyacyl-ACP dehydratase malonyl-CoA-acetyl-CoA-ACP transacylase (MAT) B-enoyl-ACP reductase