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Synthetic opioids are frequently being used for analgesia, i.e. as pain killers. While morphine or other full agonists such as fentanyl are the strongest pain killers available, partial agonists such as nalorphine or pentazocine are being used in applications requiring something intermediate in strength between morphine and basic painkillers such as aspirin. Considering a situation where both morphine and pentazocine are co-administered, select the TRUE statement(s): A. With increasing concentrations of pentazocine, the percent maximal response for morphine can be reduced to the level of pentazocine. B. The dose-response curve for morphine will shift to the right and its shape will not change (parallel rightward shift). C. The dose-response curve for morphine will shift to the left and its shape will not change (parallel leftward shift). D. The maximal efficacy of morphine alone can be exceeded. E. None of the answers here is correct.

Synthetic opioids are frequently being used for analgesia, i.e. as pain killers. While morphine or other full agonists such as fentanyl are the strongest pain killers available, partial agonists such as nalorphine or pentazocine are being used in applications requiring something intermediate in strength between morphine and basic painkillers such as aspirin. Considering a situation where both morphine and pentazocine are co-administered, select the TRUE statement(s): A. With increasing concentrations of pentazocine, the percent maximal response for morphine can be reduced to the level of pentazocine. B. The dose-response curve for morphine will shift to the right and its shape will not change (parallel rightward shift). C. The dose-response curve for morphine will shift to the left and its shape will not change (parallel leftward shift). D. The maximal efficacy of morphine alone can be exceeded. E. None of the answers here is correct.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Synthetic opioids are frequently being used for analgesia, i.e. as pain killers. While morphine or other full agonists such as fentanyl are the strongest pain killers available, partial agonists such as nalorphine or pentazocine are being used in applications requiring something intermediate in strength between morphine and basic painkillers such as aspirin. Considering a situation where both morphine and pentazocine are co-administered, select the TRUE statement(s): A. With increasing concentrations of pentazocine, the percent maximal response for morphine can be reduced to the level of pentazocine. B. The dose-response curve for morphine will shift to the right and its shape will not change (parallel rightward shift). C. The dose-response curve for morphine will shift to the left and its shape will not change (parallel leftward shift). D. The maximal efficacy of morphine alone can be exceeded. E. None of the answers here is correct. Please answer asap and type your answer and do not copy from anywhere please
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