Luisa is a carrier of the allele for Tay-Sachs but has no sign of any eye disorder in her family. She married Gerard whose mother was afflicted with retinitis pigmentosa, unlike his father. Neither of his parents has any history of Tay-Sachs disease. 1. What are the genotypes of Luisa and Gerard?  2. If they plan to have five children, what is the probability that: a. all their children will be normal? b. they will have a daughter with retinitis pigmentosa?  c. they will have a son inflicted with both conditions?  d. at least 2 will be normal? (show COMPLETE solutions for this question)

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter18: Genetics Of Behavior
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Problem 14QP: A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known...
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Luisa is a carrier of the allele for Tay-Sachs but has no sign of any eye disorder in her family. She
married Gerard whose mother was afflicted with retinitis pigmentosa, unlike his father. Neither of his
parents has any history of Tay-Sachs disease.

1. What are the genotypes of Luisa and Gerard? 

2. If they plan to have five children, what is the probability that:

a. all their children will be normal?
b. they will have a daughter with retinitis pigmentosa? 

c. they will have a son inflicted with both conditions? 
d. at least 2 will be normal? (show COMPLETE solutions for this question)

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