Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section12.4: B Lymphocytes: Antibody-mediated Immunity
Problem 2CYU
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List the functions of the antigen-binding site and Fc region of antibodies, and briefly describe how each occurs.
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Antigens are molecules that can elicit an immunological response. Each antigen includes unique surface characteristics, known as epitopes, that cause individual reactions. Antibodies (immunoglobins) are Y-shaped proteins generated by immune system B cells to respond to antigen exposure. Each antibody has a paratope that binds to a particular epitope on an antigen, similar to a lock and key binding mechanism. This binding aids in the elimination of antigens from the body, either directly or indirectly.
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