Identify the label in the correct position in the following: C-1 of acetyl CoA to malate (one cycle) 3-14C OAA + unlabeled acetyl-CoA to succinate.
Q: Acetly CoA can quickly enter the citric acid cyle by joining with a C4 compound and forming citrate.…
A: Citric acid cycle or Kreb 's cycle ---Citric acid cycle or Kreb's cycle is a metabolic process…
Q: Which of the following reactions correspond to the decarboxylation step during ketone body…
A: Ketogenesis occurs continually in a healthy person, however it occurs at a faster rate under…
Q: Which of the following intermediates are shared by ketone body synthesis and cholesterol…
A: In the mitochondria when acetyl-CoA accumulates beyond its capacity to be oxidized or used for fatty…
Q: What are the 4 steps that must happen to convert pyruvate into acetyl coA? What 3 enzymes are…
A: Pyruvate oxidation is the odd one out of the four stages of cellular respiration; it is…
Q: On these following choices, Malonyl CoA synthase, Malonyl CoA synthetase, Acetyl CoA carboxylase and…
A: The conversion of acetyl CoA to malonyl CoA takes place due to the action of enzyme Acetyl CoA…
Q: The following fatty acid enters the B-oxidation spiral. CH,(CH,)4-CH,-CH,-C-OH and the product shown…
A: Fatty acids are long-chain carboxylic acids. The long chain is aliphatic in nature that has single…
Q: The succinyl CoA to citrate pathway of the citric acid cycle is shown. Identify the missing…
A: Succinyl Co-A and the reactions given in the question are part of the TCA cycle. The TCA cycle is a…
Q: How many more acetyl CoA are generated from stearic acid than from linoleic acid during beta…
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Q: Which produces more succinyl-coA concentration: Degrading a 16:0 lipid or degrading a 17:0 lipid? Or…
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Q: If the w-carbon atom of a fatty acyl CoA molecule with a C18 chain is labeled with C14, how many…
A: Fatty acids consist of an carboxylic acid group at one end of the molecule, thus making it an acid.…
Q: Complete the following paragraph describing the fate of the second 14CO-acetyl-CoA molecule…
A: Glyoxylate cycle: This cycle involves the conversion of Acetyl CoA to Succinate for the synthesis…
Q: Step 2 of B-oxidation involves a reaction with chemistry characterized as a dehydration. B-Oxidation…
A: Introduction: The oxidation of fatty acid on the β-carbon atom is beta-oxidation. It occurs in the…
Q: Give the process/pathway where each of the following enzymes is involved.
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Q: Draw in detail the mechanism of alpha-ketoglutarate to succinyl CoA.
A: KEY WORDS :- Alpha-ketoglutarate - When alpha-ketoglutarate is oxidized, carbon dioxide is detached,…
Q: Starting with acetyl-S-enzyme-1 and malonyl-CoA, how many molecules of acetyl- CoA are needed to…
A: Fatty acid synthesis is a process of creating fatty acids from acetyl-CoA and NADPH by fatty acid…
Q: following metabolite negatively regulates pyruvate kinase? Select one: a. Fructose-1,6-Bisphosphate…
A: It is essential to regulate metabolic pathways because all are interconnected to each other. Hence,…
Q: Consider the following fatty acyl-CoA: CH3CH2CH2CH2CH2CH2CH2CH2CH=CHCH2CH=CHCH2 CH2CH2CH2CO- S-COA…
A: Beta-oxidation is the catabolic process. Here, fatty acid molecules are broken down in the…
Q: H-C FADH₂ FAD H₂O COO™ 1 C-H COO™™ Fumarate ADP ATP COO™ HO–CH CH₂ COO™ Malate NAD COO™ CH₂ CH₂ COO™…
A: TThe citric acid cycle (CAC) is the key metabolic pathway responsible for the oxidative degradation…
Q: Consider MYRISTIC ACID CH3-(CH2)12 - COOH B. How many acetyl CoA molecules are formed by complete…
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Q: Beta-Oxidation of a 15:14⁹ fatty acid will result in the production of which of the following? 7…
A: The given fatty acid is composed of 15 carbon and it has a single double bond present in it. It…
Q: difference between an acetyl CoA molecule and an acyl CoA molecule?
A: Acetyl CoA and Acyl CoA are the type of Coenzyme A which acts as a cofactor. Coenzyme A is…
Q: Consider the complete oxidation of one mole of the fatty acyl CoA of myristic acid (14:0).
A:
Q: Hexanoic acid is a 6-carbon saturated fatty acid found in goat's milk. Hexanoic acid also…
A: Fatty acids undergo degradation or beta-oxidation in the matrix of mitochondria inside the cell.…
Q: All the following amino acids are converted to succinyl-CoA except Group of answer choices Lysine…
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Q: Will an amino acid be glucogenic or ketogenic if it is catabolized to the following molecules?(a)…
A: Glucogenic amino acids are the amino acids that are converted into glucose through gluconeogenesis…
Q: Match the following metabolites with the correct metabolic pathway v Propionyl-CoA A. Kreb's cycle…
A: Answer: METABOLIC PATHWAYS: These are the seres or linked chemical pathways of metabolites which…
Q: branched chain amino acids form Succinyl CoA when catabolize
A: Catabolism of valine produce succinyl co-A.
Q: Write some alternative names of HMG-CoA?
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Q: Order the steps that results in a triacylglycerol containing two palmitic acids and one stearic…
A: The below steps are involved in fatty acid synthesis- two palmitic and one stearic acid containing…
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A: B-oxidation: It is the catabolism of fat since the bond break from 2nd/beta carbon and 3rd/gamma…
Q: In acety1 COA, what type of bond is present between the acetyl group and coenzyme A? A. thioester…
A: Acetyl-coA consist an acetyl group and coenzyme A.
Q: The structure of citrate is shown above with the carbon atoms numbered 1 through 6. If carbon atoms…
A: Krebs cycle is also known as Tricarboxylic acid cycle or Citric acid cycle. It takes place in the…
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Q: Explain why with complete examples: A- Partial carbocation formation B- Acetyl CoA has many fates
A: Partial carbocation: Carbocations are nothing but positively charged carbon atoms. Under normal…
Q: Name some HMG CoA reductase inhibitors? Please answer at your own words.
A: HMG-CoA Reductase (3-hydroxy-3-methyl-glutaryl-CoA) is the rate-limiting enzyme of the cholesterol…
Q: When transaminated, the three branched-chain amino acids (valine, leucine, and isoleucine) form…
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Q: Which of the following statements is TRUE about cholesterol biosynthesis? Group of answer choices…
A: Cholesterol biosynthesis pathway involves the conversion of the Acetyl CoA to the Acetoacetyl CoA…
Q: Describe the synthesis of palmitic acid starting from acetyl CoA and malonyl-CoA.
A: Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid…
Q: Below is an image of the Krebs cycle: acetyl-CoA oxaloacetate COASH H20 NADH NAD* H20 malate citrate…
A: The Krebs cycle, also known as the citric acid cycle or the tricarboxylic acid cycle, is one of the…
Q: Match the following metabolites with the col Propionyl-CoA A. Kreb's cycle v Dihydroxy acetone…
A: NOTE: AS PER OUR GUIDELINES WE ARE ONLY ALLOWED TO ANSWER FIRST QUESTION, PLEASE RESUBMIT THE OTHER…
Q: E-CH2-C + H* co, + CH,-C-s-COA S-COA Malonyl-CoA Acetyl-CoA Hydrolase Transferase Lyase Ligase
A: The given reaction shows that Malonyl CoA which is a 3 carbon compound is converted to acetyl CoA, a…
Q: If acetyl-CoA containing radiolabeled carbons in the acetyl group was used to synthesize leucine,…
A: Amino acids are biosynthesized from the intermediates of glycolysis, tricarboxylic acid cycle or the…
Q: Match the description on the left with the correct Coenzyme A-linked thioester from the dropdown…
A: Hi. Thank you for the question. As per the honor code, we are allowed to answer three sub-parts at a…
Q: what is the metabolic reaction\pathway in which the propionyl CoA caboxylase evzyme is involved ? (…
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Q: Which of the following is NOT produced during the reactions of acetyl-CoA formation? (only one…
A: Acetyl-CoA can be generated in either of two ways, first is oxidative decarboxylation of pyruvate…
Identify the label in the correct position in the following: C-1 of acetyl CoA to malate (one cycle) 3-14C OAA + unlabeled acetyl-CoA to succinate.
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- Identify a pathway for utilization of the four carbons of acetoacetate in cholesterol biosynthesis. Carry your pathway as far as the rate-determining reaction in cholesterol biosynthesis. Drag the appropriate labels to their respective targets. succinyl-CoA succinate acetyl-CoA CoA-SH acetoacetyl-CoA HMG-CoA 2NADP 2NADPH+ 2H acetoacetate K UHL return to a mevalonate + CoA-SHC-CH2 + H* CO, + CH,-C-S-COA S-COA Malonyl-CoA Acetyl-CoA Hydrolase Transferase Lyase LigaseBelow is an image of the Krebs cycle: acetyl-CoA oxaloacetate COASH H20 NADH NAD* H20 malate citrate fumarate isocitrate FADH2 NAD* CO2 FAD АТР NADH + ADP succinate GTP NAD+ a-ketoglutarate H20 GDP NADH + CO2 COASH succinyl CoA COASH Consider the conversion of succinate to fumarate, which is coupled with the production the electron carrier FADH2. If this reaction was NOT coupled with the production of FADH2 (and only catalyzed the conversion of succinate to fumarate), how would this impact ATP production through cell respiration? OATP production would stop because no high energy electron carriers would be produced ATP production would still occur, but there would be a much lower ATP yield because a large number of electron carriers are no longer being made ATP production would stop because without FADH2 we will no longer have electrons moving through the electron transport chain ATP production would still occur, but there would be a slightly lower ATP yield because a small number of…
- Acetly CoA can quickly enter the citric acid cyle by joining with a C4 compound and forming citrate. Meanwhile, GTP (or ATP) is generated using inorganic phosphate while succinyl CoA is converted to succinate. What is the main reason both acetly CoA and succinyl CoA can perform such work? a. Acetyl CoA and succinyl CoA both contain coenzyme A, which is a high-energy compound. b. Acetyl CoA and succinyl CoA both form an unstable thioester bond with coenzyme A. c. Acetyl CoA and succinyl CoA both bind with inorganic phosphate which is used to generate ATP (or GTP). d. Acetyl CoA and succinyl CoA both transiently form a covalent bond with the enzymes that catalyze the next reaction, pyruvate dehydrogenase and succinyl-CoA synthetase, respectively. e. Acetyl CoA and succinyl CoA use the energy collected from the electron transport chain.One of the regulators of the TCA cycle is succinyl CoA. Discuss the rationale for this molecule to be used to regulate the TCA cycle. What is the metabolic role of succinyl CoA?A biological Claisen reaction occurs in the conversion of two acetyl CoA molecules to one acetoacetyl CoA. Analyze each step of the incomplete mechanism and add the missing curved arrows. The base is abbreviated as B: in the mechanism.
- Match each of the enzymes involved in de novo pyrimidine synthesis with the correct description: _______ Dihydroorotate dehydrogenase _______ UMP synthase_______ Carbamoyl phosphate synthetase II _______ TMP synthase _______ CTP synthetase_______ Aspartate transcarbamoylase _______ PRPP synthetase (A) attaches an aspartate to an activated carbamoyl molecule(B) bifunctional enzyme that combines a nitrogenase pyrimidine ring to an activated ribose(C) catalyzes the formation of the activated ribose sugar(D) uses glutamine to add an amine to a preformed nucleotide(E) produces the first cyclic nitrogenase ring during de novo pyrimidine synthesis(F) combines bicarbonate and nitrogen from glutamine in the first step of pyrimidine ring synthesis (G) uses a folate derivative to add a methyl group to a preformed nucleotideThiolase is homologous in structure to the condensing enzyme. On the basis of this observation, propose a mechanism for the cleavage of 3-ketoacyl CoA by CoA.Which of the following most accurately describes the impact acetyl-CoA has in the cytosol of the liver cell? Acetyl CoA serves as an allosteric inhibitor of PFK Acetyl CoA serves as an allosteric inhibitor of pyruvate kinase Acetyl CoA serves as an allosteric activator of PFK Acetyl CoA serves as an allosteric activator of pyruvate kinase Acetyl CoA serves as an allosteric activator of fructose-2,6-bisphosphatase Acetyl CoA serves as an allosteric activator of PFK-2
- What are the possivble oxidation product of catalase using H2O2 as the substrate? Explain in 1-3 sentencesPart A Identify each of the following metabolic pathways. Drag the appropriate labels to their respective targets. Reset Help the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino acid to an a-keto transamination acid the combination of 2-carbon units of acetyl COA to form fatty acids oxidative deamination the removal of an amino group as NH4+ from B oxidation glutamate to yield a-ketoglutarate lipogenesis the production of ketone bodiesFatty acids are converted to their coenzyme A esters in a reversible reaction catalyzed by acyl-CoA synthetase: R-COO +ATP +COA R-C-COA +AMP + PPi a) The reaction involves two steps the first of which forms an enzyme-bound intermediate identified as the mixed anhydride of the fatty acid and AMP: R-C-O-P-O-nibose-adenine Write two chemical equations coresponding to the two steps of the reaction catalyzed by the synthetase. b) The acyl-CoA synthetase reaction as written above is readily reversible. How might the reaction be made to favor formation of fatty acyl-CoA? Write within the box. Anything outside the box will not be graded. From the