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- Explain this statement: Although 2-methoxyacetic acid (CH3OCH2COOH) is a stronger acid than acetic acid (CH3COOH), p-methoxybenzoic acid (CH3OC6H4COOH) is a weaker acid than benzoic acid (C6H5COOH).Describe the steps necessary to perform the following synthesisExplain why methyl trifluoroacetate, CF3CO2CH3, is more reactive than methyl acetate, CH3CO2CH3, in nucleophilic acyl substitution reactions.
- Please complete the following question. There is no need to provide an explaination. 20Give the major organic product(s) of the following reaction. 1) CH3CH2M9B 2) H30+ Give the major organic product(s) of the following reaction. 1) PhMgBr 2) H30+Although codeine occurs in low concentration in the opium poppy, most of the codeine used in medicine is prepared from morphine (the principal component of opium) by the following reaction. Explain why selective methylation occurs at only one OH in morphine to give codeine. Codeine is a less potent and less addictive analgesic than morphine. но. CH,0. [1 кон H [2] CH3I H. CH3 H Ho morphine H. CH3 Ho codeine
- (b) Cortisone OH H2C CH -HO- H3C Oalcohol O carbon-carbon double bond Oester Oaldehyde Ocarbon-carbon triple bond Oether O amide Ocarboxylate anion Oketone Oamine O carboxylic acid O thiol (c) Prostaglandin PGE2 COOH Но OH Oalcohol O carbon-carbon double bond Oester Oaldehyde Ocarbon-carbon triple bond Oether Oketone O amide O carboxylate anion Oamine Ocarboxylic acid O thiolPQ-19. Which phosphorus reagent is required for this reaction? (A) PPh3 (B) PPh3 (C) H PPh3 (D) PPh3Provide the reagents necessary to complete the following reactions.