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- Discuss the pathophysiological concepts of hypoperfusion and embolismDiscuss the clinical features, classifications, and causes of anaemia. Provide mehcnaims and examples. 600 wordsDescribe and compare the pathophysiology, etiology,manifestations, diagnostic tests, and treatment for each ofthe selected anemias: iron-deficiency, pernicious, aplastic,sickle cell, and thalassemia.