WEEK_6_N2112_Module_SIX_Acid_Base_Renal__1_
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Mount Royal University *
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Course
2112
Subject
Nursing
Date
May 16, 2024
Type
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54
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1
Week 6: Nursing 2112 – Module 6
Part 1: Acid Base, Alterations to Fluid and Electrolytes Part 2: Alterations to Renal Function ACID BASE
OBJECTIVES: Students should be able to:
Describe how hydrogen and bicarbonate play a role in maintaining homeostasis.
Explain the causes and characteristics of each of the acid-base disturbances.
Identify how the renal and respiratory systems work to compensate for each other.
Interpret Arterial Blood Gases.
ALTERATIONS IN FLUIDS AND ELECTROLYTES
OBJECTIVES: Students should be able to:
Distinguish between hypovolemia and hypervolemia.
Interpret and apply theoretical knowledge of the pathophysiology of conditions that cause fluid and electrolyte
imbalance.
Describe the risk factors, pathophysiology, clinical manifestations, assessments, diagnostics and management for:
Sodium, Potassium, Calcium, Magnesium and Phosphate
Explain the pharmacological and non-pharmacological interventions to prevent, manage, and alleviate
manifestations arising from the alterations to fluid and electrolyte balance and alterations in renal and urinary
function.
Describe the nursing process regarding a patient at risk of fluid/electrolyte imbalance.
ALTERATIONS IN URINARY AND RENAL FUNCTION
OBJECTIVES: Students should be able to:
Differentiate between lower and upper UTI’s.
Discuss the management of urinary incontinence and urinary retention.
Identify the difference between acute kidney injury (AKI) and chronic kidney disease (CKD).
Assess patients at risk for both of these conditions using case scenarios and chart data.
Week Six N2112
Developed by the Teaching Team
Concept
Content
Acid-Base Balance
Causes of the four disturbances/imbalances
S/S of imbalance
Management of acid-base imbalance
Related Lab values
Fluid Balance
Hyper/hypovolemia
Iso, hyper, hypotonic solutions
Nursing process of Fluid imbalance
Related Lab values
Electrolyte Balance
Sodium, Potassium, Calcium, Mg and Phos.
Manifestations and Management
Related Lab values
Urinary and Renal Alterations
Upper and lower infections
Incontinence and retention
AKI
CKD
Intro to Dialysis
Nursing process for Renal patients
2
Determine appropriate nursing interventions for the prevention and treatment of these conditions
Interpret and apply theoretical knowledge of the pathophysiology of conditions that cause
alterations in the renal and urinary system using critical thinking and clinical judgment for nursing practice.
Develop a nursing care plan for a client experiencing renal disease or injury.
Describe why a patient would have dialysis, the similarities and differences between hemodialysis and peritoneal dialysis, and potential complications of each.
PREPARATION
Terminology for Review: The following terms will be utilized within this module and throughout the course. Please familiarize
yourself with these terms and be able to define them.
Acid-Base Acid -anything that donates a H+
Base
-anything that donates OH-
Acidosis
Acidosis - A condition of acidity or low pH (below 7.35) of the blood
- high hydrogen ion concentration.
ANP
Atrial natriuretic peptide (ANP)
-
a hormone secreted by the heart when blood pressure rises
- fine-tunes blood pressure and sodium-water balance of the body
What does ANP do - inhibit the renin-angiotensin-
aldosterone mechanism
- It blocks renin and aldosterone secre-tion
-inhibits other angiotensin-induced mechanisms that enhance water and Na+ reabsorption
-Consequently, ANP’s overall
influence is to decrease blood
pressure by allowing Na+ (and
Baroreceptors
When are baroreceptors activated -When arterial blood pressure rises, it activates baroreceptors
Where are baroreceptors -These stretch receptors are located in the carotid sinuses (dila-tions in the internal carotid arteries, which provide the major blood supply to the brain)
- in the aortic arch
- in the walls of nearly every large artery of the neck and thorax
What happens when baroreceptors are stretched -When stretched, baroreceptors send a rapid stream of impulses to the cardiovascular center, inhibiting the vasomotor and cardio-acceleratory centers and stimulating the cardioinhibitory center. The result is a decrease in blood pressure Two mechanisms bring this about:
●Vasodilation. Decreased output from the vasomotor center allows arterioles and veins to dilate. Arteriolar vasodilation reduces total peripheral resistance, so MAP falls. Venodila-tion Metabolic alkalosis -When excessive loss of metabolic acids occurs, bicarbonate concentration increases, causing metabolic alkalosis
Oliguria -decreased urine output -30mL/hr or less
Osmoreceptor -Structure sensitive to osmotic pressure or
concentration of a solution.
Renin-angiotensin-aldosterone-
system
The renin-angiotensin-aldosterone mechanism influences both blood volume and
blood pressure by regulating the release of aldosterone and therefore Na+ and water reabsorption by the kidneys. 1. When blood pressure (or blood vol-ume) falls, specialized cells of the juxtaglomerular complex in the kid-neys are excited.
2. These cells respond by releasing renin into the blood.
3. Renin splits off part of the plasma protein angiotensinogen (an0je-o-ten9sin-o-jen), triggering an enzy-matic cascade that forms Week Six N2112
Developed by the Teaching Team
3
water) to flow out of the body in
urine (natriuretic 5 pro-ducing salty
urine).
Anuria
Anuria
-Abnormally low urinary output (less
than 50 ml/day)
ADH
ADH
-ADH causes the kidneys to retain water.
Alkalosis
Alkalosis
-A condition of basicity or high pH (above 7.45) of the blood
- low hydrogen ion concentration
Arterial blood gas
Azotemia
Azotemia -(increased nitrogen levels in the blood)
-abnormal concentration of nitrogenous wastes in the blood
shifts blood to the venous reservoirs, which decreases venous return and cardiac output.
●Decreased cardiac output. Impulses to the cardiac centers inhibit sympathetic activity and stimulate parasympathetic activity, reducing heart
rate and contractile force. As CO falls, so does MAP
Dialysis
Dialysis -DIffusion of solute(s) through a semipermeable membrane.
Diffusion
-movement of particles from a higher concentration to a lower concentration
Diuresis
Urine production Electrolytes Electrolytes are solutes in body fluids
Filtration Hypovolemia
Hypervolemia
Metabolic acidosis
-
Metabolic acidosis occurs as the body's cells switch to anaerobic metabolism
-In response to metabolic acidosis, heart rate and stroke volume increase in an attempt to improve tissue angiotensin II, which stimulates the glomerulosa cells to release aldosterone.
Aldosterone -released in response to low Na+ or high K+ blood levels
Its pri-mary target is the kidney tubules, where it
●Stimulates Na+ reabsorption (causing increased blood volume and blood pressure because water follows Na+)
●Causes K+ secretion into the tubules for elimination from the body
Respiratory acidosis
- when a person breathes shallowly -when gas exchange is hampered by diseases such as pneumonia, cystic fibrosis, or emphysema
-CO2 accumulates in the blood
-Thus, respiratory acidosis is characterized by falling blood pH and rising PCO2
-While respiratory acidosis is frequently associated with
respiratory system pathology
Respiratory alkalosis
-results when carbon dioxide is eliminated from the body faster than it is produced
-This is called hyperventilation (deeper and faster breathing than needed to remove CO2; p. 855)
- results in the blood becoming more alkaline
-respiratory alkalosis is often due to stress or pain
Week Six N2112
Developed by the Teaching Team
4
perfusion.
Sodium Potassium Pump
Uremia
uremia
-clinical syndrome associ-ated with renal failure is called uremia (literally “urine in the blood”) -fatigue
-anorexia, nausea
-mental changes, and muscle cramps
-While uremia was once attributed to accumulation of nitro-genous wastes (particularly urea), we now know that urea is not especially toxi
multiorgan failure from uremia is caused by the interplay of multiple factors. These include
-
ionic and hormo-nal imbalances (including anemia due to lack of erythropoietin; p. 648)
- as well as metabolic abnormalities and accumulation of various toxic molecules that interfere with normal metabolism
Recall Previous Concepts from Biology
Normal fluid and electrolyte balance and distribution.
Osmosis and osmolality.
Normal homeostatic mechanisms for regulation of fluids.
Determine which patient populations are at an increased risk for fluid and electrolyte imbalances.
Required Readings:
Adams, M.P., Urban, C.Q., Sutter, R.E., El-Hussein, M. and J. Osuji, J. (2021), Pharmacology for nurses: A pathophysiological approach, Third Canadian Edition
. North York, ON: Pearson Canada Inc.
For all pharmacology also review the Nursing Considerations section for each class of medication.
Chapters 52, 53
Week Six N2112
Developed by the Teaching Team
5
Power-Kean, K., Zettel, S., El-Hussein, M.T., ,Huether, S.E., McCance, K.L., Brashers, V.L. & Rote, N.S. (2022). Understanding pathophysiology (2nd Canadian edition)
. Milton, ON, Canada: Elsevier.
Chapter 5 (Fluid and Electrolytes, Acids and Bases)
Chapter 29 (Structure and Function of the Renal and Urological Systems) – This should be a review.
Chapter 30 (Alterations of Renal and Urinary Tract Function)
EL Hussein, M. & Osuji,J. (2020). Brunner & Suddarth’s Canadian Textbook of Medical-Surgical Nursing (4
rd
Ed.).
Wolters Kluwer.
Philadelphia.
Chapters 44, 45, 46
Content Study Guide
: All of this material is testable, whether covered in class or not.
The following content questions are meant to augment your learning objectives. These questions should direct your readings and help you sort out the required content, as well as integrate the content from your required readings. Use the required readings to prepare for class and help you to participate in the discussion and application of this information. Often,
the lecture slides/materials will help to answer some of these questions for you. Print off your lecture materials and use them
alongside this content study guide. Acid Base
1.
What is the role of the Hydrogen ion (H+) in maintaining homeostasis?
The concentration of hydrogen ions in body fluids
-approximately 0.000 000 1 mg/L
-This number, which may be expressed as 10−7mg/L, is indicated as pH 7.0
pH facts -- acidity or alkalinity of a solution
-As the pH changes 1 unit (e.g., from pH 7.0 to pH 6.0), the [H+] ([H+] = hydrogen ion concentration) changes tenfold
-The greater the [H+], the more acidic the solution and the lower the pH. The lower the [H+], the more alkaline or basic the solution and the higher the pH. In biological fluids
-a pH of less than 7.4 is defined as acidic and a pH greater than 7.4 is defined as alkaline, or basic
Hydrogen ion is needed to maintain
-membrane integrity - the speed of metabolic enzyme reactions
2.
What are the common causes of acid-base disturbance?
3.
What is the pathophysiology and management of each acid-base disturbance?
Week Six N2112
Developed by the Teaching Team
6
UP Pg 128-129
Acid-Base Imbalances
Pathophysiological changes in the concentration of hydrogen ion in the blood lead to acid-base imbalances.
acidemia
-pH of arterial blood is less than 7.4
acidosis -A systemic increase in hydrogen ion concentration or a loss of base is termed acidosis
alkalemia
-the pH of arterial blood is greater than 7.4
alkalosis
-A systemic decrease in hydrogen ion concentration or an excess of base is termed alkalosis Acidosis and alkalosis may be caused by -may be caused by metabolic or respiratory processes
arterial blood gases
-Acid-base imbalances are assessed using measurement of arterial blood gases
- which includes the reporting of pH, PaCO2, and HCO Figure 5-13 Metabolic Acidosis
In metabolic acidosis
-
concentrations of non–carbonic acids increase - bicarbonate lost from ECF - cannot be regenerated by the kidney (Table 5-10).
Metabolic acidosis can occur either quickly, as in
-lactic acidosis caused by poor perfusion - hypoxemia
Metabolic acidosis can occur s slowly over an extended time, as in
-renal failure
-diabetic ketoacidosis
-starvation (anion gap acidosis).
Week Six N2112
Developed by the Teaching Team
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Related Questions
diuretic,
~electrolyte,
~hyper/hypokalemia
~hyper/hyponatremia
List foods choices high in potassium
2. List a few basic nursing interventions required when a client receives either a diuretic or a potassium replacement
3. Describe what milli-equivalents (mEq) denotes
4. Identify common fat and water soluble vitamins and minerals
5. Describe the value of taking iron/calcium and other vitamin supplements and specific patient teaching criteria regarding taking them.
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question: What could be the possible nursing interventions and rationale that could be done? (4 rationale and 4 nursing interventions)
Objectives:
1. The patient will relieve pain
2. The patient will be able to maintain fluid volume
3. The patient will have normal stool in 1-3 days
4. The patient will be able to regain and additionally work on his nourishment with assistance of appropriate comprehension of the food options to help his digestion.
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TASK:Create a conceptual map using the case scenarios as guide. Conceptual map should include pathophysiology, medical diagnosis, signs and symptoms, and risk factors, if any. Nursing diagnosis, nursing interventions, medical management (medication and procedures), expected outcomes.
A 61- year old male, long standing type 2 diabetic and hypertensive, with end stage renal disease secondary to diabetic nephopathy on maintenance thrice weekly hemodialysis since the last 20- months started developing acute onset of chills, rigors, acute anxiety, vomiting and unexplained abdominal pain about ½- 1 hour into the dialysis session. These episodes which had not occurred earlier, had started from the previous one month and caused acute distress to the patient, necessitating request for early termination of dialysis. The patient denied any complaints home except for severe itching, which has started at approximately at the same time. No new medications had been initiated in the…
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RENAL DISORDERS
TASK: Create a conceptual map using the case scenarios as guide. Conceptual map should include pathophysiology, medical diagnosis, signs and symptoms, and risk factors, if any. Nursing diagnosis, nursing interventions, medical management (medication and procedures), expected outcomes
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Main nursing diagnosis: Risk of fluid volume depreciation as evidenced by nausea, vomiting and decreased fluid ingestion.
(MAKE A GENERALIZED STATEMENT OF EACH NURSING INTERVENTIONS)
1. EFFICIENCY
2. APPROPRIATENESS
3. ADEQUACY
4. ACCEPTABILITY
Interventions:
1. The nurse will give a quiet and relaxed environment and teach the patient of breathing technique to keep away the stress.
2. The nurse will evaluate the fluid ratio of the patient to make sure the fluid replenishment to adjust the fluid loss during vomiting and decreased fluid intake.
3. The nurse will encourage the client to drink 180 ml of water alongside with prescribed medications.
4. The nurse will have diet plan and ask to pick the diet with the helpof the nutritionist to get information about the food intake that he needs to stop triggering symptoms.
5. The nurse will observe and record the frequency, sum, time, and attributes of stool and for any presence of hastening factors
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Signature Assignment: End Stage Kidney Disease Case Analysis
The goal of this assignment is to show that you understand the importance of the liver, pancreas, and kidneys in the proper functioning of the human body.
Sarah, a 63-year-old female with a past medical history significant for diabetes mellitus, cirrhosis, gout, and a 30-pack a year smoking history, presents to the emergency room with chest pain revealing pericarditis in the echocardiogram, secondary to recently diagnosed end-stage renal disease. Physical examination reveals yellowish discoloration to the skin and sclera, multiple bruises, and 2+ bilateral edema. Sarah reports weakness lasting more than three weeks. Her medications include Glisten, a new drug for diabetes that causes ATP sensitive potassium channels to close, thereby releasing insulin.
Her recent laboratory results are as follows:
CBC
Sodium
126 mEq/L
Glucose
220 mmol/L
Calcium
7.1 mg/dl
Red blood cell count
3.9 cells / ul…
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ASAP
Topic: Chronic kidney disease
Question: Identify the role of nutrition/eating habit strategies that can help to prevent the condition and how these strategies can be effective
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NEED HELP WITH #4
N.R. is a 49-year-old lumber worker admitted to the emergency department after a severe laceration of his left thigh. He lost about 4 units of blood prior to effective control of bleeding and closure of the wound. He received several hundred milliliters of normal saline during the procedure. Postsurgical clinical data are as follows: vital signs lying down, HR 115, BP 98/60, RR 28; sitting, HR 140, BP 92/62, RR 28; Hct 22, Hb 8, PaO2 90, SaO2 98% breathing room air. N.R. continues to have significant oozing from his sutured wound postoperatively, prompting his physician to order a coagulation screen that has the following results: platelet count 250,000, bleeding time more than 10 min, PT and aPTT within normal ranges.
Discussion Questions
In view of N.R.’s history and vital signs, do you think he is hypovolemic? Support your conclusion.
Calculate N.R.’s arterial oxygen content (CaO2) using the following formula: CaO2 = (PaO2 × 0.003) + (Hb × SaO2 × 1.34). What…
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Assessment
Direction: Read the following item carefully. Write TRUE if the statement is correct and FALSE if the statement is incorrect.
1. If you use a household or kitchen spoon to measure liquid medicines, you can be sure you will get the right dose.
2.
You can't be harmed by over-the-counter medicines. After all, you can
buy them without a doctor's prescription. It's okay to take two medicines with the same active ingredient at the 3.
same time.
4. It's alright to use someone else's prescription medicine if you have the same symptoms he or she had when he or she got it. It's also safe to take your leftover prescription medicine later if you get 5.
sick again.
6. It's okay to take more medicine than what is directed on the label if you are very sick.
medicine, an active ingredient is what relieves a person's The Drug Facts label tells you what symptoms the medicine treats. 8.
7.
In a
symptoms.
9. 10. The Drug Facts label gives you the dosage information. A pharmacist…
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QUESTIONS:
Explain what happens to urine flow rate, specific gravity and urinary excretion of
chloride in each group. Explain the physiological mechanisms involved (Ex:
ADH stimulated or inhibited because ...) in the results from each group:
2. Salt and Water Group (Potato chips and water) – (Isotonic)
urine flow rate (v)
Specific Gravity
Chloride content (ucL)
Urinary Excretion of Chloride (UECL)
ADH
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Nursing diagnosis : Risk of imbalanced fluid volume in NCP Planning(short term goal and long term goal),Intervention ( independent and dependent) Rationale,and Evaluation.
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Critical thinking questions:
1. Evaluate Frances' fluid volume and electrolyte status. Which physiological assessment findings support your analysis? Which lab results support your analysis? What is the most likely etiology of these imbalances?
2. Explain the reasons for Frances' ECG changes?
3. Analyze the ABG results. What is the etiology of the primary imbalance? Is the body compensating for this imbalance?
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Edema Case Study Questions
The following four patients all have severe edema for different reasons. Your challenge is to explain the cause of the edema. In each case, try to explain the edema in terms of either an increase or a decrease in one of the four pressures that cause bulk flow at capillaries. A picture may be useful.
Patient 1: Mr. Taylor
Mr. Taylor is a 66 year old alcoholic who has been drinking for years. During the past month he has gained over 25 pounds due to water retention. He exhibits swelling in all areas of the body. He has recently been admitted to the hospital and diagnosed with end stage liver failure.
What is the connection between the liver failure and his edema?
Which capillary pressure is altered and how does it cause edema? Hint: consider the functions of the liver, particularly the ones that affect blood composition.
Patient 2: Mrs. So
Mrs. So is a 28 year old visiting her OB in the 26th week of her pregnancy. She is experiencing varicose veins and…
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Medication 2:
Order: Biaxin (Clarithromycin) 15 mg/kg/day divided into 2 doses for a child weighing 50
lbs
Available:
DRUG DOSAGE CALCULATIONS REVIEW WORKSHEET
Lab Day 3
NDC 0074-3163-13
14 days. DO NOT REFRIGERATE.
After mixing, store at 15° to 30°C (59° to 86° F) and use within
shake space. Keep tightly closed.
Shake well before each use. Oversize bottle provides
May be taken before, after or with meals.
02-7716-R5
58
SPECIMEN
BETWEEN ARROWS
TEAR PERFORATION
Store granules at 15° to 30°C (59° to
86°F).
CONSTITUTING INSTRUCTIONS:
VOLUME OF WATER: 55 mL
Measure the required volume of
water using a graduated cylinder.
Add half the volume of water to the
bottle and shake vigorously. Add
the remainder of water to the bottle
and shake.
Contains 2.5 g clarithromycin.
When mixed as directed, each
teaspoonful (5 ml) contains:
in a fruit punch-flavored, aqueous
vehicle.
DOSAGE MAY BE ADMINISTERED
WITHOUT REGARD TO MEALS.
Usual dose: Children: 15 mg/kg/day
divided in 2 equal doses. See…
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CONCEPTS 1: ASSIGNMENTS
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ASSIGNMENT 1: DEFINE & COMPARE THE FOLLOWING TERMS
TOPICAL CONCEPTS
- Acid-Base Balance
- Oxygenation
- Fluid-Electrolytes
. Cognition
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What is th pathophysiology overview (acidosis or alkalosis? what type? why?), Clinical manifestations (signs & symptoms), Needed assessments, Lab work & diagnostics needed, Nursing interventions and care, Treatments, and Patient teaching for Crohn's disease.
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RON is suspected of DKA. Formulate a plan of education for Ron's wife, so she will better understand his condition and be able to assist him to manage those days when is unwell. What areas would you cover? How would you ascertain her understanding?
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PatientAge: 72 Gender: Male Height: 172 cm Weight: 78 kgThe doctor's order is Potassium Chloride 40meq in 1L to run for 8 hours for the patient. Based on the Renal Drug Handbook 3rd Edition, the right rate of administration of potassium chloride is the following.
● Infusion up to 20mmol potassium per hour except in an extreme hypokalaemic emergency where some units give up to 40mmol/hour with cardiac monitoring● Give IV solution well diluted (not exceeding 40mmol/500mL) for peripheral administration.● Mix IV solutions thoroughly to avoid the layering effect● Some units give more concentrated solution centrally: 100–200mmol/100mL sodium chloride 0.9% or glucose 5%, but at a rate not more than 20mmol/hour
Does the doctor's order comply with the renal drug handbook?
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Case Study 3 – Congestive Heart Failure
Dottie is a 78-year old CHF patient. She has been exercising with your facility for several years now. She had a CABGx3 in 2020. She came in today with a 5 lb. weight gain since yesterday when she weighed on her home scale this morning. Her meds include- Lipitor, Procardia, and Lasix. (Cholesterol, Calcium channel blocker Hypertension, and Diuretic, respectively)
Her blood pressure is 132/88 and her HR = 102; Her weight is 196, up from 191 when last measured. She is a pleasant, overweight individual who enjoys walking on the treadmill and visiting with other members of your facility.
1. What are specific considerations for someone with CHF and exercise? How is the exercise prescription any different from the apparently healthy adult prescription?
2. What is your biggest concern with Dottie today and how would you handle this concern(s)?
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Question:Make nursing care plan(ncp) for a kidney failure patient
Past health history: constipation for the last 7 days accompanied by difficulty of breathing (DOB) and Abdominal pain.
Present Health history:
chief complaint of Abdominal pain. Prior to admission, facial edema and bipedal edema was notice during physical assessment.
Laboratory:
Temperature 36°c, Pulse Rate -127, Respiratory Rate- 22,Blood Pressure -120/90,URIC ACID :10.20 mg/dL,CREATININE :1.33 mg/dL
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What is the the pathophysiology overview (acidosis or alkalosis? what type? why?), Clinical manifestations (signs & symptoms), Needed assessments, Lab work & diagnostics needed, Nursing interventions and care, Treatments, and Patient teaching for pneumonia
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What is the the pathophysiology overview (acidosis or alkalosis? what type? why?), Clinical manifestations (signs & symptoms), Needed assessments, Lab work & diagnostics needed, Nursing interventions and care, Treatments, and Patient teaching for asthma
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A client with hypoparathyroidism complains of numbness and tingling in his fingers and around the mouth. The nurse would assess for what electrolyte imbalance?A. HyponatremiaB. HypocalcemiaC. HyperkalemiaD. HypermagnesemiaRationale:Reference/s:
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ASSESSMENT
4
A nurse reviews the drug history of a client who has been prescribed disopyramide for the treatment of an arrhythmia. Which of the following drugs, if taken concurrently, can decrease the serum levels of disopyramide?
1. Erythromycin
2. Quinidine
3. Thioridazine
4. Rifampicin
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Kestabie.. oualuai
3-An 8-year-old client is admitted to the hospital after being hit by
car while riding a bicycle. The nurse´s assessment reveals the
following findings: pale, cool arms and legs, capillary refill time
of 6 seconds, heart rate of 135 beats/minute, and blood
pressure of 100/80 mmHg The client is crying and asking for
something to drink. Which should diagnosis the nursing do
first?
1-Neuromuscular impairment.
2-Having a reaction to an antibiotic.
3-Developing circulatory failure.
4-Responding normally to stress
Retake
II
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Discuss the nursing implications for caring for a patient undergoing continuous renal replacement therapy (CRRT).
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Medication 1:
• Order: Ceclor (cefaclor) 100 mg p.o. q8h is ordered for a child weighing 32 lb. The
recommended dosage is 20 to 40 mg/kg/day divided q8h.
Medication Label:
NDC 61442-173-02
Directions for Mixing Add 53 ml of water in
two portions to dry mixture in the bottle. Shake
well after each
CEFACLOR
Each 5 ml (Approx one Oral Suspension, USP
125 mg anhyhydrate equivalent to P
contain Cefaclor L
Oversize bottle provides extra space for shaking
Store in a refrigerator. May be kept for 14 days
without significant loss of potency
closed Discard unused portion after 1
Usual Dose:.
125 mg per 5 mL
Pediatric Patients-20 mg/kgiday (40 mg kg per day
in ottis media) in three divided doses every hours
Adults-250 mg
See Iterature for
hours
Prior to Mixing, store at 20 to 25°C (68 to
77F) (See USP Controlled Room Temperature)
Protect from moisture
dosage information
Botte contains a total of Cefaclor Monohydrate
equivalent to 1.875 g anhydrous cefactor in a dry
strawberry
y flavored mixture…
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INSTRUCTIONS:
Read and analyze the Case scenario.
QUESTIONS:
How would you assess for dehydration?
What electrolyte imbalance(s) can occur in patients taking furosemide (Lasix)?
What relationship exists between this patient’s furosemide, digoxin, and potassium levels?
CASE ANALYSIS
A 65-year-old male client has lived alone for the past 3 years. A year ago, he was hospitalized for an MI, which resulted in heart failure. He is compliant with her medications, which include digoxin (Lanoxin) 0.125 mg daily, furosemide (Lasix) 40 mg daily, and potassium (K-Dur) 20 mEq daily.
Recently, he ran out of his potassium and thought that because it was “just a supplement,” it would be OK to go without it until the next time he went to town to fill the prescription. He has not taken her potassium for a week.
Today, he comes into the clinic with generalized weakness, fatigue, nausea, and diarrhea. Her BP is 100/60, pulse 95 bpm and slightly irregular, RR 18, and temp 97.2 °F. Blood is drawn and…
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The nurse cares for a client who has a positive Trousseau's sign The nurse identifies that this is most likely a manifestation of what electrolyte imbalance
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PHARMACOLOGY IN PRACTICE
MANAGING NEEDS
A nurse is caring for a client with renal dysfunction. The PHCP has prescribed a metolazone drug for the client. What should the nurse monitor in the client before administering the drug? Select all that apply.
1. Serum cholesterol levels
2. Levels of serum electrolytes
3. Fluid loss every hour
4. Creatinine clearance levels
5. BUN level
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Section
Name
EXERCISE
Date
Instructor
18
THE URINARY SYSTEM
Critical Thinking and Review Questions
1. List the structures through which urine passes on its way to the outside of the body,
starting with the medulla of the kidney.
Which structures rely on fluid pressure for the movement of urine?
Which structures rely on muscle action for the movement of urine?
2. Match the organ to its description or function.
Urinary bladder
stores urine
a.
Ureter
b. carries urine to the outside of the body
Urethra
c.
collects urine and funnels it into the ureter
Renal pelvis
d.
carries urine to the bladder
3. Match the structure to its description or function.
Glomerulus
carries urine through the medulla of the kidney
a.
Proximal tubule
b.
wavy tube found farther from the glomerular capsule
Distal tubule
actively reabsorbs most nutrients
с.
d. collects glomerular filtrate
ball of leaky capillaries
Glomerular capsule
Collecting duct
e.
4. List the structures of the nephron where filtration occurs.
List…
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Fluid and Electrolytes Case Study
Patient Profile:
Frances, a 78 years old that lives alone, is admitted to the hospital because of weakness and
confusion. She has a history atrial fibrillation and chronic heart failure (HF). On admission it is
noted that her at home medications include Digoxin (Lanoxin), Furosemide (Lasix), Metoprolol,
Diltiazem and Levothyroxine.
Objective Data:
Neurologic: Confused; slow to questioning; generalized weakness; states she has trouble
focusing his vision- people look green with halo's
Cardiovascular: BP 100/59; HR 55 irregular; peripheral pulses weak; ECG indicates Atrial
fibrillation with controlled ventricular response
Pulmonary: Respirations at 12/min; shallow
Skin: decreased turgor; dry mucous membranes
Laboratory Results:
Digoxin level
Electrolytes
●
• Mag+
CI-
BUN
CBC
Na+
K+
ABG
● RBC
● WBC
●
Creatinine
Glucose
CO2
Hemoglobin
Hematocrit
Platelets
pH
PaO2
PaCO2
HCO3-
1.0 ng/ml
134 mEq/L
2.5 mEq/L
1.2 mEq/L
88 mEq/L
42 mg/dL
0.9 mg/dL
122 mg/dL…
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2. Prepare client teaching handouts for each of the following topics:
Client who is scheduled for a cystoscopy
Treatment and prevention of recurrent cystitis
Care of a urinary diversion
3. Develop a chart that compares and contrasts acute renal failure and
end-stage renal disease (ESRD).
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