The net current flowing through an ion channel at a cell's resting potential flows in one direction determined by the equilibrium potentials of the ions that flow through it. Given this, how is it possible for hair cells in the cochlea to alternately hyperpolarize and depolarize during sound waves when they only have a single mechanosensitive ion channel (TMC1/TMC2 heteromer)?
The net current flowing through an ion channel at a cell's resting potential flows in one direction determined by the equilibrium potentials of the ions that flow through it. Given this, how is it possible for hair cells in the cochlea to alternately hyperpolarize and depolarize during sound waves when they only have a single mechanosensitive ion channel (TMC1/TMC2 heteromer)?
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter6: The Peripheral Nervous System: Afferent Division; Special Senses
Section: Chapter Questions
Problem 8RE
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