QUESTION 11 Which of the following statements about RNA interference pathways and mechanisms is FALSE? O A Investigators can load RISC and/or RITS complexes with artificial, designed RNAS in order to specifically target and silence a gene of interest as a way to see what the effect of that gene is when its expression is silenced. O B. Only a small section of a small interfering RNA, called the 'seed' sequence, is actually used to identify nucleic acid targets that are to be silenced. OC Eukaryotic RNA interference pathways do not regulate genes from the genome itself (Le. endogenous genes), they only respond to external infection events such as invading viruses. OD. The piRNA pathway processes small RNAS out of long noncoding RNA transcripts and is important for suppression of repetitive element movement in germ cells. O E The micro (n RNA pathway and the short interfering (si) pathways load small RNAS into RISC or RITS complexes.

Human Anatomy & Physiology (11th Edition)
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QUESTION 11
Which of the following statements about RNA interference pathways and mechanisms is FALSE?
O A Investigators can load RISC and/or RITS complexes with artificial, designed RNAS in order to specifically
target and silence a gene of interest as a way to see what the effect of that gene is when its expression
is silenced.
O B. Only a small section of a small interfering RNA, called the 'seed' sequence, is actually used to identify
nucleic acid targets that are to be silenced.
OC. Eukaryotic RNA interference pathways do not regulate genes from the genome itself (i.e. endogenous
genes), they only respond to external infection events such as invading viruses.
The piRNA pathway processes small RNAS out of long noncoding RNA transcripts and is important for
suppression of repetitive element movement in germ cells.
OD.
O E. The micro (n RNA pathway and the short interfering (si) pathways load small RNAS into RISC or RITS
complexes.
Transcribed Image Text:QUESTION 11 Which of the following statements about RNA interference pathways and mechanisms is FALSE? O A Investigators can load RISC and/or RITS complexes with artificial, designed RNAS in order to specifically target and silence a gene of interest as a way to see what the effect of that gene is when its expression is silenced. O B. Only a small section of a small interfering RNA, called the 'seed' sequence, is actually used to identify nucleic acid targets that are to be silenced. OC. Eukaryotic RNA interference pathways do not regulate genes from the genome itself (i.e. endogenous genes), they only respond to external infection events such as invading viruses. The piRNA pathway processes small RNAS out of long noncoding RNA transcripts and is important for suppression of repetitive element movement in germ cells. OD. O E. The micro (n RNA pathway and the short interfering (si) pathways load small RNAS into RISC or RITS complexes.
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