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Different transcription factors are expressed in different cell types
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- A change in what type of cell is most likely to cause a mutation that can be inherited? O brain gamete O heart O skinA chromosome contains many different genes that are transcribed into different ___ . a. proteins b. polypeptides c. RNAs d. a and bWhich of the following includes all of the others? a. homeotic genes b. master regulators c. SRY gene d. PAX6
- Enhanced Spatial Learning in Mice With an Autism Mutation Autism is a neurobiological disorder with symptoms that include impaired social interactions and stereotyped patterns of behavior. Around 10 percent of autistic people have an extraordinary skill or talent such as greatly enhanced memory. Mutations in neuroligin 3, an adhesion protein that connects brain cells to one another, have been associated with autism. One mutation changes amino acid 451 from arginine to cysteine. In 2007, Katsuhiko Tabuchi and his colleagues genetically modified mice to carry the same arginine-to-cysteine substitution in their neuroligin 3. Mice with the mutation had impaired social behavior. To test spatial learning ability, the mice were placed in a water maze: a deep pool of warm water in which a platform is submerged a few millimeters below the surface. The platform is not visible to swimming mice. Mice do not particularly enjoy swimming, so they locate a hidden platform as fast as they can. When tested again, they can remember its location by checking visual cues around the edge of the pool. How quickly they remember the platforms location is a measure of spatial learning ability (FIGURE 15.18). FIGURE 15.18 spatial learning ability in mica mutation in neuroligin 3 (R451C), compared with unmodified (wild-type) mica. 1. In the first, how many days did it take unmodified mice to learn to find the location of the hidden platform within 10 seconds?Mutations in genes can cause a loss of inhibition? O Proto-oncogenes O Oncogenes O Tumor suppressor genes O CyclinsWhich Is not one of the ways that a proto-oncogene can become converted into an oncogene? O Introduction of a mutation O Mutating a tumor suppressor gene simultaneously O Relocation to an area of DNA that has more active gene expression O An increase in copy number
- E VG ✓H NA MATEN Match each letter (A through G) to its description. B A ya pada saat ada para a H F காலிமாம்ம் P S —— 1. Receptor 2. RNA 3. Lysosome 4. DNA 5. Ribosome 6. Ligand 7. Kinase domain 8. Nucleus 9. Mitochondria 10. Phosphorylated transcription factor 11. Dephosphorylated transcription factor 12. Plasma membraneA cell picks up mutations that allow it to move past the G1 and G2 checkpoints even if its growth factor is not present, These mutations a tightly to other cells and the extracellular matrix. As a result, this cell would .. O die O form a benign tumor form a malignant tumor that metasticizes O form a mass of normal tissueWhat is the normal function of tumor suppressor genes? O prevent cells from going through mitosis O promote cells to grow out of control prevent cells trom growing out of control O stop the cells cycle
- Ultraviolet light may cause DNA damage. Any change to DNA is known as a "mutation". How might such damage affect Synthesis? the cell won't be able to copy its DNA the cell will not be able to go through G2 without going through S first the cell will copy the mutated DNA and pass it onto the newly created cells the cell will enter G0The process of cell modification from a generalized cell to one that performs a specific task is known as recombinant DNA O gene expression O cell differentiation gene developmentWhat is the normal function of tumor suppressor genes? prevent cells from going through mitosis O promote cells to grow out of control O prevent cells from growing out of control O stop the cells cycle