A woman has just been diagnosed with breast cancer. Her doctor tells her that while cancer is a multifactorial disease, she carries the breast cancer susceptibility gene, BRCA1. One of her two identical twin 19-year-old daughters is afraid that she also may have inherited the gene. -What considerations would you give her daughter who is worried about inheriting the cancer gene?

A woman has just been diagnosed with breast cancer. Her doctor tells her that while cancer is a multifactorial disease, she carries the breast cancer susceptibility gene, BRCA1. One of her two identical twin 19-year-old daughters is afraid that she also may have inherited the gene. -What considerations would you give her daughter who is worried about inheriting the cancer gene?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter1: A Perspective On Human Genetics

Section: Chapter Questions

Problem 9QP: If your father were diagnosed with an inherited disease that develops around the age of 50, would...

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A woman has just been diagnosed with breast cancer. Her doctor tells her that while cancer is a multifactorial disease, she carries the breast cancer susceptibility gene, BRCA1. One of her two identical twin 19-year-old daughters is afraid that she also may have inherited the gene.-What considerations would you give her daughter who is worried about inheriting the cancer gene?
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Mrs. Ortez has type III breast cancer and is now concluding the trial portion of a certain research study about this condition. She has responding well to the series of neoplastic medications and is currently in remmision. The researchers and her surgeon have informed both mrs Ortez and her husband that there is the possibility that her unique type of cancer could have a genetic foundation. Most at risk would be her 8 year old daughter, through both her 10 yr old and 2 yr old sons could carry the genetic mutation for this cancer. How do you, as her primary nurses, address her concerns for possible genetic testing of her children? Should the identification of the children's risk as possible carriers of this specific gene be identified at this time? Should the testing be even considered to be done at this time?
Although cancer is not a contagious disease in humans or other vertebrates, there have been rare cases in which cancers have spread from one organism to another. Describe three cases of these contagious cancers and what conditions might have led to their appearance. For an introduction to this topic, see http:// www.cancer.org/cancer/cancerbasics/is-cancer-contagious.
I understand how nuclear factor-kB (NFKB) works in the inflammatory response but what is the mechanism by which it causes cancer?
Our government has finite funds to devote to cancer research.Discuss which of the following areas of research you think shouldreceive the most funding.A. Identifying and characterizing oncogenes and tumorsuppressorgenesB. Identifying agents in our environment that cause cancerC. Identifying viruses that cause cancer D. Devising methods aimed at killing cancer cells in the bodyE. Informing the public of the risks involved in exposure tocarcinogensIn the long run, in which of these areas would you expect successfulresearch to be the most effective in decreasing human mortalitydue to cancer?
Despite all that we know about cancer today, some types of cancers are still increasing in frequency. Lung cancer among nonsmoking women is one of these. What reason(s) might there be for this increasing problem?
A genetic predisposition to developing cancer is usually inheritedas a dominant trait. At the level of cellular function, are the allelesinvolved actually dominant? Explain why some individuals whohave inherited these dominant alleles do not develop cancer duringtheir lifetimes.
What is meant by the "two-hit" model of cancer development? Describe this theory in detail and explain why this makes sense with the observation that cancer is typically seen in people who are >60 years of age.
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Which of the following effectively describes the situation of someone with an inherited predisposition to cancer such as familial adenomatous polyposis or BRCA-associated familial breast cancer? Choose all that apply a) If they get malignant cancer, somatic mutations will not have been a factor b) Their cancer will most likely arise in their germ cells, not their somatic cells c) None of the answers effectively describes the situation d) Every cell of their body contains a gain-of-function allele of an oncogene e) Most cells in their body contain multiple cancer-causing mutations f) Every cell of their body contains a defective, loss-of-function allele of a tumor suppressor gene